Karel Frasch

TL;DR: The findings indicate that disrupted intrinsic connectivity of a speech-related network could underlie persistent AVHs in patients with schizophrenia, and the occurrence of hallucinatory symptoms seems to modulate RSNs associated with attention and executive control.

TL;DR: The findings partially support the current concept of dopaminergic dysfunction in schizophrenia, suggesting a rather hyperactive mesolimbic dopamine system and reduced prefrontal activation, at least in partially remitted patients treated with atypical antipsychotics.

TL;DR: Analysis of functional magnetic resonance imaging, a verbal working memory task and multivariate statistical techniques suggest that within two temporally anticorrelated network states, patients with schizophrenia exhibit increased and persistent dorsolateral prefrontal and hippocampal connectivity during WM performance.

TL;DR: The results indicate that regional abnormalities in brain structure may offer an account for some impaired cognitive domains in patients with schizophrenia, while other cognitive domains may remain relatively less affected by volumetric alterations.

TL;DR: In this paper, an overview of diagnostic reliability, symptomatology, outcome, neurobiology and treatment of schizoaffective disorder is provided, where common neurobiological factors were found across the traditional diagnostic categories.