K
Karen Chance
Researcher at University of York
Publications - 1
Citations - 234
Karen Chance is an academic researcher from University of York. The author has contributed to research in topics: Dissociation (chemistry) & Monomer. The author has an hindex of 1, co-authored 1 publications receiving 224 citations.
Papers
More filters
Journal ArticleDOI
Insulin at pH 2: structural analysis of the conditions promoting insulin fibre formation.
Jean L. Whittingham,David J. Scott,Karen Chance,Ashley J. Wilson,John T. Finch,Jens Brange,Guy Dodson +6 more
TL;DR: Results suggest that acid conditions increase the susceptibility of the molecule to conformational change and dissociation, and enhance the rate of fibrillation by providing a charged environment in which the attractive forces between the protein molecules is increased.