K
Karen M. Hauda
Researcher at Johns Hopkins University
Publications - 7
Citations - 893
Karen M. Hauda is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Immune system & Immunotherapy. The author has an hindex of 7, co-authored 7 publications receiving 887 citations. Previous affiliations of Karen M. Hauda include Massachusetts Institute of Technology & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Use of murine models of cytokine-secreting tumor vaccines to study feasibility and toxicity issues critical to designing clinical trials
Elizabeth M. Jaffee,Audrey J. Lazenby,Janet Meurer,Fray F. Marshall,Karen M. Hauda,Christy Counts,Herbert Hurwitz,Jonathan W. Simons,Hyam I. Levitsky,Drew M. Pardoll +9 more
TL;DR: The efficacy of freeze/thawed vaccine cells is demonstrated and peak levels of granulocyte-macrophage colony-stimulating factor (GM-CSF) are far below levels expected to result in significant side effects in patients.
Journal ArticleDOI
Bioactivity of Autologous Irradiated Renal Cell Carcinoma Vaccines Generated by Ex Vivo Granulocyte-Macrophage Colony-Stimulating Factor Gene Transfer
Jonathan W. Simons,Elizabeth M. Jaffee,Christine E. Weber,Hyam I. Levitsky,William G. Nelson,Michael A. Carducci,Audrey J. Lazenby,Lawrence K. Cohen,Christy C. Finn,Shirley M. Clift,Karen M. Hauda,Lisa A. Beck,Kristin M. Leiferman,Albert H. Owens,Steven Piantadosi,Glenn Dranoff,Richard C. Mulligan,Drew M. Pardoll,Fray F. Marshall +18 more
TL;DR: A Phase I trial evaluating the safety and the induction of immune responses in patients with metastatic renal cell carcinoma (RCC) was reported in this paper. But, no evidence of autoimmune disease was observed.