Showing papers in "The Journal of Urology in 1998"

TL;DR: Oral sildenafil is an effective, well-tolerated treatment for men with erectile dysfunction and is associated with improved erectile function in the dose-response study.

TL;DR: The data support the proposal that enhancement of penile erection by sildenafil in patients with erectile dysfunction involves potentiation of the NO-stimulated cGMP signal mediating relaxation of cavernosal smooth muscle during sexual stimulation.

TL;DR: Genitourinary symptoms are a frequent reason for office visits by younger and older men, and prostatitis is a common diagnosis, despite a report that less than 10% of prostatritis cases are bacterial, a much higher proportion of men in whom prost atitis is diagnosed receive antimicrobials.

TL;DR: In this article, the evolution of the surgical technique for anatomic radical prostatectomy is described, which has improved surgical exposure, lowered blood loss, reduced urinary incontinence, and made it possible to preserve potency.

TL;DR: A strong positive association was observed between IGF-I levels and prostate cancer risk, independent of baseline prostate-specific antigen levels, which may have implications for risk reduction and treatment.

TL;DR: Dysfunctional elimination syndromes are common and are often unrecognized in children with primary reflux and are associated with delayed reflux resolution and an increased rate of breakthrough urinary tract infection, which leads to reimplantation surgery.

TL;DR: In men with early stage and advanced prostate cancer physician ratings of patient symptoms do not correlate well with patient self-assessments of health related quality of life, and urologists should attempt to elucidate more completely the components of patientquality of life after the diagnosis and treatment of prostate cancer.

TL;DR: Two consecutive sets of transrectal ultrasound guided sextant biopsies of the prostate performed in a single office visit represent a cost-effective biopsy strategy for men presenting with an abnormal digital rectal examination and/or elevated serum PSA.

TL;DR: Positive margins increase the risk of progression and correlate with decreased cancer specific and overall survival, and there is no consensus on the management of positive margins.

TL;DR: Transrectal ultrasound guided needle biopsy is safe for diagnosing prostate cancer with few major but frequent minor complications and recent use of aspirin or nonsteroidal anti-inflammatory drugs is not an absolute contraindication for this procedure.

TL;DR: A variety of nongerm cell histologies, including sarcoma, adenocarcinoma, primitive neuroectodermal tumor and leukemia, may occur in association with germ cell tumor, and surgical resection is the mainstay of therapy.

TL;DR: In patients with cardiac risk factors who are undergoing noncardiac surgery, the perioperative maintenance of normothermia is associated with a reduced incidence of morbid cardiac events and ventricular tachycardia.

TL;DR: The meta-analysis demonstrated that yohimbine is superior to placebo in the treatment of erectile dysfunction and should be considered as initial pharmacological intervention.

TL;DR: Stage specific followup guidelines are reported based on the evaluation of the pattern of recurrence in 286 patients treated for local N0 or Nx renal cell carcinoma and confirmed that the risk of metastatic renal cell cancer is stage dependent.

TL;DR: Overall stress incontinence was cured or improved in 92% of the patients with at least 1-year followup and Fascial pubovaginal sling is an effective treatment for all types of stressincontinence with acceptable long-term efficacy.

TL;DR: This retrospective analysis suggests that extending the limits of pelvic lymph node dissection from the bifurcation of the common iliac vessels to the bIFurculation of the aorta improves the recurrence-free survival rate for patients undergoing radical cystectomy for bladder cancer confined to the bladder wall.

TL;DR: In this article, the authors assess the effects of aging on renal function by utilizing cross-sectional studies and institutionalized elderly subjects, with their attendant drawbacks, and conclude that the morphological and functional changes of aging tend to be less marked than previously thought.

TL;DR: The findings suggest that this 23% incidence of false-negative biopsies represents significant cancer and is important to consider in treatment modalities in which prostate biopsy may be performed to determine response to therapy.

TL;DR: It is suggested that bladder cancers with high pRb expression do not show the tumor suppressor effects of the protein, and alteration in both p53 and pRB may act in cooperative or synergistic ways to promote tumor progression.

TL;DR: An algorithm using unenhanced computerized tomography (CT) for the management of acute flank pain and suspected ureteral obstruction accurately determines the presence or absence of u reterolithiasis in patients with acute flankPain.

TL;DR: In this paper, p27 protein expression was evaluated in 86 patients with clinical stage T1-2 prostate cancer who were treated with radical prostatectomy and the absence or presence of p27 was then correlated with biochemical relapse in univariate and multivariate analyses.

TL;DR: Among men with symptoms of urinary obstruction and prostatic enlargement, treatment with finasteride for four years reduces symptoms and prostate volume, increases the urinary flow rate, and reduces the risk of surgery and acute urinary retention.

TL;DR: This report is meant to provide guidance to those centers that would like to initiate clearance procedures but have difficulty in choosing appropriate methodology.

TL;DR: Anatomic radical retropubic prostatectomy with the nerve sparing modification can be performed with good cancer control and is significantly associated with lower preoperative PSA, lower grade and localized pathological stage and all cause survival.

TL;DR: Chronic diffusion of urinary potassium into the bladder interstitium may induce sensory symptoms, damage tissue and be a major toxic factor in the pathogenesis of interstitial cystitis and intravesical potassium sensitivity is a reliable method for detecting abnormal epithelial permeability.

TL;DR: Preliminary evidence is provided that calcitriol effectively slows the rate of PSA rise in select cases, although dose dependent calciuric side effects limit its clinical usefulness.

TL;DR: Dilation and internal urethrotomy are useful in a select group (approximately 70% of all patients) who are stricture-free at 3 months, and of whom 50 to 60% will remain strictures-free up to 48 months.

TL;DR: Mouse germ cells in vitro were susceptible to anti-Fas antibody-induced death, and the survival of rat germ cells was increased after disruption of FasL by antisense oligonucleotide treatment, arguing for the importance of the Fas system in maintaining testicular homeostasis.

TL;DR: Technological advances in the design and construction of the AMS 800 have dramatically decreased the reoperation and failure rates and provide an excellent long-term solution and increased continence in correctly selected patients with urinary incontinence.