K
Kari Auranen
Researcher at University of Turku
Publications - 101
Citations - 5892
Kari Auranen is an academic researcher from University of Turku. The author has contributed to research in topics: Population & Vaccination. The author has an hindex of 29, co-authored 93 publications receiving 5053 citations. Previous affiliations of Kari Auranen include National Institutes of Health & University of Helsinki.
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Journal ArticleDOI
Social contacts and mixing patterns relevant to the spread of infectious diseases.
Joël Mossong,Niel Hens,Mark Jit,Philippe Beutels,Kari Auranen,Rafael T. Mikolajczyk,Marco Massari,Stefania Salmaso,Gianpaolo Scalia Tomba,Jacco Wallinga,Janneke C. M. Heijne,Malgorzata Sadkowska-Todys,Magdalena Rosinska,W. John Edmunds +13 more
TL;DR: This study provides the first large-scale quantitative approach to contact patterns relevant for infections transmitted by the respiratory or close-contact route, and the results should lead to improved parameterisation of mathematical models used to design control strategies.
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The fundamental link between pneumococcal carriage and disease
TL;DR: A review of the evidence supporting pneumococcal carriage at the individual level as an immediate and necessary precursor to pneumonia disease is provided in this article, where the authors emphasize the role of information on vaccine carriage in vaccine trials and in public health decision-making.
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Invasiveness of serotypes and clones of Streptococcus pneumoniae among children in Finland.
William P. Hanage,Tarja Kaijalainen,Ritva Syrjänen,Kari Auranen,Maija Leinonen,P. Helena Mäkelä,Brian G. Spratt +6 more
TL;DR: The results demonstrate the invasive phenotype of the serotype 14 variant of the Spain9V-3 clone and differences between members of the same serogroup in invasive disease potential.
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Between-Strain Competition in Acquisition and Clearance of Pneumococcal Carriage—Epidemiologic Evidence From a Longitudinal Study of Day-Care Children
TL;DR: The authors employed longitudinal data on pneumococcal carriage in Danish day-care children to analyze between-serotype competition and found that acquisition of other serotypes in already-colonized hosts was weak and clearance of any single serotype was not affected by simultaneous carriage of otherserotypes.
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Nasopharyngeal colonization: a target for pneumococcal vaccination.
TL;DR: The accumulated experience shows that the herd immunity, due to PCV, is partly offset by replacement of the vaccine serotypes by other, nonvaccine serotypes, so the possibility of more virulent nonvaccines arising cannot be ignored and should be the focus of continued surveillance.