K
Karine Lambou
Researcher at University of Montpellier
Publications - 1
Citations - 21
Karine Lambou is an academic researcher from University of Montpellier. The author has contributed to research in topics: Innate immune system & Coxiella burnetii. The author has an hindex of 1, co-authored 1 publications receiving 6 citations.
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Modulation of innate immune signaling by a Coxiella burnetii eukaryotic-like effector protein
Melanie Burette,Julie Allombert,Karine Lambou,Ghizlane Maarifi,Sébastien Nisole,Elizabeth Di Russo Case,Fabien Blanchet,Cedric Hassen-Khodja,Stéphanie Cabantous,James E. Samuel,Eric Martinez,Matteo Bonazzi +11 more
TL;DR: A new effector protein, NopA (nucleolar protein A), is discovered, which localizes at nucleoli of infected cells and perturbs nucleocytoplasmic transport by manipulating the intracellular gradients of the GTPase Ran, and is an important regulator of the innate immune response allowing Coxiella to behave as a stealth pathogen.