K
Karyn N. Johnson
Researcher at University of Queensland
Publications - 76
Citations - 5637
Karyn N. Johnson is an academic researcher from University of Queensland. The author has contributed to research in topics: Wolbachia & Virus. The author has an hindex of 27, co-authored 73 publications receiving 5023 citations. Previous affiliations of Karyn N. Johnson include Commonwealth Scientific and Industrial Research Organisation & University of Alabama at Birmingham.
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Journal ArticleDOI
A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium
Luciano Andrade Moreira,Inaki Iturbe-Ormaetxe,Jason A. L. Jeffery,Guangjin Lu,Alyssa T. Pyke,Lauren M. Hedges,Bruno Coelho Rocha,Sonja Hall-Mendelin,Andrew Day,Markus Riegler,Leon E. Hugo,Karyn N. Johnson,Brian H. Kay,Elizabeth A. McGraw,Andrew F. van den Hurk,Andrew F. van den Hurk,Peter A. Ryan,Scott Leslie O'Neill +17 more
TL;DR: It is suggested that this Wolbachia-mediated pathogen interference may work synergistically with the life-shortening strategy proposed previously to provide a powerful approach for the control of insect transmitted diseases.
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Wolbachia and Virus Protection in Insects
TL;DR: It is demonstrated that Drosophila melanogaster flies infected with Wolbachia are less susceptible to mortality induced by a range of RNA viruses and might be exploited in future strategies to reduce transmission of pathogens by insects.
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Variation in antiviral protection mediated by different Wolbachia strains in Drosophila simulans.
TL;DR: Protection from virus-induced mortality was associated with a delay in virus accumulation, but some Wolbachia-infected flies were tolerant to high titres of DCV, indicating that Wolbachio-mediated antiviral protection is not ubiquitous.
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Symbiont-mediated protection in insect hosts
TL;DR: Recent theoretical predictions and experimental observations of symbiont-mediated protection in insects are reviewed and what is known about the molecular mechanisms that underpin symbionts protection are described.
Journal ArticleDOI
Dietary Cholesterol Modulates Pathogen Blocking by Wolbachia
Eric P. Caragata,Edwige Rances,Lauren M. Hedges,Alexander W. Gofton,Karyn N. Johnson,Scott Leslie O'Neill,Scott Leslie O'Neill,Elizabeth A. McGraw +7 more
TL;DR: It is observed that flies reared on cholesterol-enriched diets infected with the Wolbachia strains wMelPop and wMelCS exhibited reduced pathogen blocking, and a shift toward greater virulence in the presence of cholesterol also corresponded to higher viral copy numbers in the host.