K
Katalin Mikecz
Researcher at Rush University Medical Center
Publications - 159
Citations - 8464
Katalin Mikecz is an academic researcher from Rush University Medical Center. The author has contributed to research in topics: Arthritis & Cartilage. The author has an hindex of 52, co-authored 156 publications receiving 7997 citations. Previous affiliations of Katalin Mikecz include Shriners Hospitals for Children & University of Illinois at Chicago.
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Impaired cumulus mucification and female sterility in tumor necrosis factor-induced protein-6 deficient mice
Csaba Fülöp,Sándor Szántó,Durba Mukhopadhyay,Tamás Bárdos,Rajesh V. Kamath,Marylin S. Rugg,Anthony J. Day,Antonietta Salustri,Vincent C. Hascall,Tibor T. Glant,Katalin Mikecz +10 more
TL;DR: It is shown that Recombinant TNFIP6 is able to catalyze the covalent transfer of heavy chains to hyaluronan in a cell-free system, restore the expansion of Tnfip6-null cumulus cell-oocyte complexes in vitro, and rescue the fertility in TNfip 6-null females.
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Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis.
TL;DR: The evidence shows that the CD44 receptor plays a critical role in governing the migration of inflammatory leukocytes into the extravascular compartment of the synovium in murine arthritis, and the administration of such an antibody abrogates tissue swelling and leukocyte infiltration, two major components of inflammation.
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Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology.
TL;DR: Clinical and morphologic features of the disease correlated well with radiologic analysis and with an increased deposition of 99mTc-methylene diphosphonate (determined by radionuclide imaging).
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Genetics of rheumatoid arthritis - A comprehensive review
TL;DR: Pharmacogenomics identified SNPs or multiple genetic signatures that may be associated with responses to traditional disease-modifying drugs and biologics.
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Chondrocyte Matrix Metalloproteinase-8 HUMAN ARTICULAR CHONDROCYTES EXPRESS NEUTROPHIL COLLAGENASE
Ada A. Cole,Susan Chubinskaya,Barbara L. Schumacher,Klaus Huch,Gabriella Cs-Szabo,Jianling Yao,Katalin Mikecz,Karen A. Hasty,Karen A. Hasty,Klaus E. Kuettner +9 more
TL;DR: The presence of both MMP-8 protein and message in cartilage supports the concept that neutrophil collagenase could be the enzyme described as “aggrecanase.”