K
Kate Fletcher
Researcher at University of Birmingham
Publications - 40
Citations - 2733
Kate Fletcher is an academic researcher from University of Birmingham. The author has contributed to research in topics: Randomized controlled trial & Population. The author has an hindex of 15, co-authored 40 publications receiving 2556 citations.
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Journal ArticleDOI
Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial
Jonathan Mant,FD Richard Hobbs,Kate Fletcher,Andrea K Roalfe,David Fitzmaurice,Gregory Y.H. Lip,Ellen Murray +6 more
TL;DR: These data support the use of anticoagulation therapy for people aged over 75 who have atrial fibrillation, unless there are contraindications or the patient decides that the benefits are not worth the inconvenience.
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Systematic review and individual patient data meta-analysis of diagnosis of heart failure, with modelling of implications of different diagnostic strategies in primary care
Jonathan Mant,Jenny Doust,Andrea K Roalfe,Pelham Barton,Martin R. Cowie,Paul Glasziou,David Mant,Richard J McManus,Roger Holder,Jonathan J Deeks,Kate Fletcher,M. Qume,S. Sohanpal,Sharon Sanders,F. D. R. Hobbs +14 more
TL;DR: A simple clinical rule was developed: in a patient presenting with symptoms such as breathlessness in whom heart failure is suspected, refer directly to echocardiography if the patient has a history of myocardial infarction or basal crepitations or is a male with ankle oedema; otherwise, carry out a BNP test and refer for echOCardiography depending on the results of the test.
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Impact of age and sex on primary preventive treatment for cardiovascular disease in the West Midlands, UK: cross sectional study
TL;DR: Low use of statins in older people highlights the need for a stronger evidence base and clearer guidelines for people aged over 75, and there were no consistent differences in prescribing trends by sex.
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Warfarin Versus Aspirin for Prevention of Cognitive Decline in Atrial Fibrillation Randomized Controlled Trial (Birmingham Atrial Fibrillation Treatment of the Aged Study)
Nahal Mavaddat,Andrea K Roalfe,Kate Fletcher,Gregory Y.H. Lip,FD Richard Hobbs,David Fitzmaurice,Jonathan Mant +6 more
TL;DR: No evidence is found that anticoagulation confers clinically important protection over aspirin against cognitive decline as measured by the Mini-Mental State Examination in atrial fibrillation in the first 33 months of treatment other than that provided by preventing clinical stroke.
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Performance of stroke risk scores in older people with atrial fibrillation not taking warfarin: comparative cohort study from BAFTA trial
TL;DR: Current risk stratification schemes in older people with atrial fibrillation have only limited ability to predict the risk of stroke, and there could be a pragmatic rationale for classifying all patients over 75 as “high risk” until better tools are available.