K
Katrin E. Wiese
Researcher at University of Amsterdam
Publications - 14
Citations - 1624
Katrin E. Wiese is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Wnt signaling pathway & Promoter. The author has an hindex of 7, co-authored 13 publications receiving 1199 citations. Previous affiliations of Katrin E. Wiese include University of Würzburg.
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Journal ArticleDOI
mScarlet: a bright monomeric red fluorescent protein for cellular imaging
Daphne S. Bindels,Lindsay Haarbosch,Laura van Weeren,Marten Postma,Katrin E. Wiese,Marieke Mastop,S. Aumonier,S. Aumonier,Guillaume Gotthard,Guillaume Gotthard,Antoine Royant,Antoine Royant,Mark A. Hink,Theodorus W. J. Gadella +13 more
TL;DR: The engineering of mScarlet is reported, a truly monomeric red fluorescent protein with record brightness, quantum yield, and fluorescence lifetime and it is especially useful as a Förster resonance energy transfer (FRET) acceptor in ratiometric imaging.
Journal ArticleDOI
Activation and repression by oncogenic MYC shape tumour-specific gene expression profiles
Susanne Walz,Francesca Lorenzin,Jennifer P. Morton,Katrin E. Wiese,Björn von Eyss,Steffi Herold,Lukas Rycak,Hélène Dumay-Odelot,Saadia A. Karim,Marek Bartkuhn,Frederik Roels,Torsten Wüstefeld,Matthias Fischer,Martin Teichmann,Lars Zender,Chia-Lin Wei,Owen J. Sansom,Elmar Wolf,Martin Eilers +18 more
TL;DR: Changes in MYC levels activate and repress specific sets of direct target genes that are characteristic of MYC-transformed tumour cells that have considerable prognostic value, suggesting that different cellular responses to physiological and oncogenic MyC levels are controlled by promoter affinity.
Journal ArticleDOI
Wnt signalling: conquering complexity
TL;DR: This Primer discusses how instrumental developmental biology has been in unravelling specific aspects of Wnt signalling, and its impact on current clinical research and the development of novel treatments for cancer.
Journal ArticleDOI
A MYC-Driven Change in Mitochondrial Dynamics Limits YAP/TAZ Function in Mammary Epithelial Cells and Breast Cancer
Björn von Eyss,Laura A. Jaenicke,Roderik M. Kortlever,Roderik M. Kortlever,Nadine Royla,Katrin E. Wiese,Sebastian Letschert,Leigh-Anne McDuffus,Markus Sauer,Andreas Rosenwald,Gerard I. Evan,Gerard I. Evan,Stefan Kempa,Martin Eilers +13 more
TL;DR: Mouse models and human pathological data show that MYC enhances AMPK and suppresses YAP/TAZ activity in mammary tumors and a phospholipase of the mitochondrial outer membrane, PLD6, is the mediator of MYC activity.
Journal ArticleDOI
The Role of MIZ-1 in MYC-Dependent Tumorigenesis
Katrin E. Wiese,Susanne Walz,Björn von Eyss,Elmar Wolf,Dimitris Athineos,Owen J. Sansom,Martin Eilers +6 more
TL;DR: It is proposed that the interaction of MYC with the zinc finger protein MIZ-1 mediates resistance to antimitogenic signals and mediates both oncogenic functions ofMYC as well as tumor-suppressive responses to oncogenicity levels of MyC.