K
Kayhan Bolelli
Researcher at Ankara University
Publications - 27
Citations - 329
Kayhan Bolelli is an academic researcher from Ankara University. The author has contributed to research in topics: Pharmacophore & Benzoxazole. The author has an hindex of 8, co-authored 25 publications receiving 248 citations. Previous affiliations of Kayhan Bolelli include Mercer University.
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Journal ArticleDOI
Synthesis, biological evaluation and 2D-QSAR analysis of benzoxazoles as antimicrobial agents.
Tugba Ertan,Ilkay Yildiz,Betul Tekiner-Gulbas,Kayhan Bolelli,Ozlem Temiz-Arpaci,Semiha Özkan,Fatma Kaynak,Ismail Yalcin,Esin Aki +8 more
TL;DR: A new series of 5(or 6)-nitro/amino-2-(substituted phenyl/benzyl)benzoxazole derivatives synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, Pseudomonas aeruginosa, Escherichia coli, Candida albicans and their drug-resistant isolate.
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Vibrational spectroscopic (FT-IR, FT-Raman, ^{1}H NMR and UV) investigations and computational study of 5-nitro-2-(4-nitrobenzyl) benzoxazole
J.B. Bhagyasree,Hema Tresa Varghese,C. Yohannan Panicker,Jadu Samuel,Christian Van Alsenoy,Kayhan Bolelli,Ilkay Yildiz,Esin Aki +7 more
TL;DR: The optimized molecular structure, vibrational frequencies, corresponding vibrational assignments of 5-nitro-2-(4-Nitrobenzyl) benzoxazole have been investigated experimentally and theoretically using Gaussian09 software package and the calculated geometrical parameters are in agreement with that of similar derivatives.
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Quantum Mechanical Studies of Three Aromatic Halogen-Substituted Bioactive Sulfonamidobenzoxazole Compounds with Potential Light Harvesting Properties
Y. Sheena Mary,Tugba Ertan-Bolelli,Renjith Thomas,Akhil R. Krishnan,Kayhan Bolelli,Esin Nagihan Kasap,Tijen Önkol,Ilkay Yildiz +7 more
TL;DR: Three different organic compounds, 2-phenyl-5-(4-trifloromethyl phenyl sulfonamido) benzoxazole (PTPS), 2-(4chlorobenzyl)-5-(2,4-dinitrophenylsulfonamide)benzoxazoles (CNSB) and 2-( 4-fluorobenzyl)-...
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Synthesis and biological evaluation of 2-substituted-5-(4-nitrophenylsulfonamido)benzoxazoles as human GST P1-1 inhibitors, and description of the binding site features.
Tugba Ertan-Bolelli,Yaman Musdal,Kayhan Bolelli,Serap Yilmaz,Yasemin Aksoy,Ilkay Yildiz,Esin Aki-Yalcin,Ismail Yalcin +7 more
TL;DR: The design and synthesis of some novel sulfonamide‐containing benzoxazoles, which are able to inhibit human GST P1‐1 are reported, and 2‐(4‐chlorobenzyl)‐5‐ (4‐nitrophenylsulfonamido)benzoxazole (5 f) was found as the most active hGST P 1‐1 inhibitor, with an IC50 value of 10.2 μM, showing
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Binding site feature description of 2-substituted benzothiazoles as potential AcrAB-TolC efflux pump inhibitors in E. coli.
Serap Yilmaz,G. Altinkanat-Gelmez,Kayhan Bolelli,D. Guneser-Merdan,M. Ufuk Over-Hasdemir,Esin Aki-Yalcin,Ismail Yalcin +6 more
TL;DR: A set of BSN-coded 2-substituted benzothiazoles tested alone and in combinations with ciprofloxacin against the AcrAB-TolC overexpressor Escherichia coli AG102 clinical strain indicated that the BSN compounds did not show intrinsic antimicrobial activity when tested alone, but when used in combination with CIP, a reversal in the antibacterial activity of CIP was observed.