K
Kazuhiko Aida
Researcher at Iwate University
Publications - 25
Citations - 709
Kazuhiko Aida is an academic researcher from Iwate University. The author has contributed to research in topics: Sphingolipid & Ceramide. The author has an hindex of 15, co-authored 24 publications receiving 625 citations. Previous affiliations of Kazuhiko Aida include Obihiro University of Agriculture and Veterinary Medicine.
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Journal ArticleDOI
Dietary sphingolipids improve skin barrier functions via the upregulation of ceramide synthases in the epidermis
Jingjing Duan,Tatsuya Sugawara,Mayumi Hirose,Kazuhiko Aida,Shota Sakai,Aoi Fujii,Takashi Hirata +6 more
TL;DR: The results show that dietary GluCer and SM accelerate the recoveries of damaged skin barrier functions and suggest that the effects of dietary sphingolipids might be due to the activation of ceramide synthesis in the skin, rather than the direct reutilization of dietary spending.
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Intestinal absorption of dietary maize glucosylceramide in lymphatic duct cannulated rats
Tatsuya Sugawara,Tsuyoshi Tsuduki,Saeko Yano,Mayumi Hirose,Jingjing Duan,Kazuhiko Aida,Ikuo Ikeda,Takashi Hirata +7 more
TL;DR: Results indicate that dietary glucosylceramide originating from higher plants is slightly absorbed in the intestine and is incorporated into ceramide structures in the intestinal cells, however, it appears that the intact form of sphingoid bases is not reutilized well in the tissues.
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Analysis of glucosylceramides from various sources by liquid chromatography-ion trap mass spectrometry.
TL;DR: The typical signals which are characteristic for the sphingoid base moieties were observed while the isomers could not be distinguished in the liquid chromatography-ion trap mass spectrometry method.
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Prevention of Aberrant Crypt Foci Formation by Dietary Maize and Yeast Cerebrosides in 1,2-Dimethylhydrazine-treated Mice
Kazuhiko Aida,Kazuhiko Aida,Mikio Kinoshita,Mikio Kinoshita,Mikio Tanji,Mikio Tanji,Tatsuya Sugawara,Masahiko Tamura,Masahiko Tamura,Jisaburo Ono,Norimichi Ueno,Masao Ohnishi,Masao Ohnishi +12 more
TL;DR: It is demonstrated that DMH-induced ACF formation could be inhibited in mouse large intestine by maize and yeast cerebrosides, which may serve to suppress colon carcinoma in humans.
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Effect of Dietary Wine Pomace Extract and Oleanolic Acid on Plasma Lipids in Rats Fed High-Fat Diet and Its DNA Microarray Analysis
Keita Yunoki,Gaku Sasaki,Yoshihiko Tokuji,Mikio Kinoshita,Akihiko Naito,Kazuhiko Aida,Masao Ohnishi +6 more
TL;DR: Assessment of the concentration of oleanolic acids in pomace and its influence on the levels of plasma lipids in rats fed a high-fat diet and on hepatic gene expression suggested that administration of OA or PEE could ameliorate obesity-induced insulin resistance, as well as prevent hyperlipidemia.