K
Kazuma Yamakawa
Researcher at Osaka Medical College
Publications - 173
Citations - 3687
Kazuma Yamakawa is an academic researcher from Osaka Medical College. The author has contributed to research in topics: Sepsis & Disseminated intravascular coagulation. The author has an hindex of 27, co-authored 136 publications receiving 2306 citations. Previous affiliations of Kazuma Yamakawa include Osaka University & Osaka Prefectural Medical Center.
Papers
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Journal ArticleDOI
Post-intensive care syndrome: its pathophysiology, prevention, and future directions
Shigeaki Inoue,Junji Hatakeyama,Yutaka Kondo,Toru Hifumi,Hideaki Sakuramoto,Tatsuya Kawasaki,Shunsuke Taito,Kensuke Nakamura,Takeshi Unoki,Yusuke Kawai,Yuji Kenmotsu,Masafumi Saito,Kazuma Yamakawa,Osamu Nishida +13 more
TL;DR: The pathophysiology, prevention, and future directions of Post‐intensive care syndrome are outlined, which includes performance of the ABCDEFGH bundle, which incorporates the prevention of delirium, early rehabilitation, family intervention, and follow‐up from the time of ICU admission to the time to discharge.
Journal ArticleDOI
Efficacy and safety of anticoagulant therapy in three specific populations with sepsis: a meta-analysis of randomized controlled trials.
TL;DR: Most anticoagulant therapy has failed to demonstrate a survival benefit in the overall sepsis population, but survival benefit was observed only in the septic disseminated intravascular coagulation (DIC) population.
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Recombinant human soluble thrombomodulin in severe sepsis: a systematic review and meta‐analysis
Kazuma Yamakawa,Morio Aihara,Hiroshi Ogura,Hiroki Yuhara,Toshimitsu Hamasaki,Takeshi Shimazu +5 more
TL;DR: Although recombinant human soluble thrombomodulin (rhTM) is a widely used novel anticoagulant agent for disseminated intravascular coagulation (DIC) in Japan, its clinical efficacy in sepsis‐induced DIC has not been demonstrated convincingly.
Journal ArticleDOI
Treatment effects of recombinant human soluble thrombomodulin in patients with severe sepsis: a historical control study
Kazuma Yamakawa,Satoshi Fujimi,Tomoyoshi Mohri,Hiroki Matsuda,Yasushi Nakamori,Tomoya Hirose,Osamu Tasaki,Hiroshi Ogura,Yasuyuki Kuwagata,Toshimitsu Hamasaki,Takeshi Shimazu +10 more
TL;DR: It is found that rhTM administration may improve organ dysfunction in patients with sepsis-induced DIC, and further clinical investigations are necessary to evaluate the effect of rhTM on the pathophysiology of sepsiastic DIC.
Journal ArticleDOI
Early rehabilitation to prevent postintensive care syndrome in patients with critical illness: a systematic review and meta-analysis.
Ryota Fuke,Toru Hifumi,Yutaka Kondo,Junji Hatakeyama,Tetsuhiro Takei,Kazuma Yamakawa,Shigeaki Inoue,Osamu Nishida +7 more
TL;DR: Early rehabilitation improved only short-term physical-related outcomes in patients with critical illness, and did not improve the long-term outcomes of PICS as characterised by EQ5D and SF-36 PF.