K
Kazunari Nagayoshi
Researcher at University of Tsukuba
Publications - 9
Citations - 1392
Kazunari Nagayoshi is an academic researcher from University of Tsukuba. The author has contributed to research in topics: Haematopoiesis & Interleukin 3. The author has an hindex of 9, co-authored 9 publications receiving 1365 citations.
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Journal ArticleDOI
In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells.
Seiji Okada,Hiromitsu Nakauchi,Kazunari Nagayoshi,Shin-Ichi Nishikawa,Yasusada Miura,Toshio Suda +5 more
TL;DR: Although c-kit is found both on the primitive hematopoietic stem cells and progenitors, Sca-1+ cells are more primitive and respond better than ScA-1- cells to a combination of hematopolietic factors, including SCF and stromal cells.
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Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule
Seiji Okada,Hiromitsu Nakauchi,Kazunari Nagayoshi,Shin Ichi Nishikawa,Yasusada Miura,Toshio Suda +5 more
TL;DR: The data show that the c- kit molecule is expressed in primitive stem cells and plays an essential role in the early stages of hematopoiesis.
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Human primitive hematopoietic progenitor cells are more enriched in KITlow cells than in KIThigh cells
Yuji Gunji,Mitsuru Nakamura,Osawa Hisao,Kazunari Nagayoshi,Hiromitsu Nakauchi,Yasusada Miura,Masayoshi Yanagisawa,Toshio Suda +7 more
TL;DR: Results indicate that primitive progenitors are more enriched in the KITlow population and that the KIThigh population contains many GM-committed progenitor cells, which emphasize the pivotal role of the K IT and SCF interaction in hematopoiesis.
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Expression and function of adhesion molecules on human hematopoietic stem cells: CD34+ LFA-1- cells are more primitive than CD34+ LFA-1+ cells.
Yuji Gunji,Mitsuru Nakamura,T Hagiwara,Hayakawa K,H Matsushita,Osawa Hisao,Kazunari Nagayoshi,Hiromitsu Nakauchi,Masayoshi Yanagisawa,Yasusada Miura +9 more
TL;DR: Data provide a rationale for the administration of anti- LFA-1 antibody after bone marrow transplantation for reducing the graft failure and clarify the role of adhesion molecules in HSCs.
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Lymphokine requirement for the generation of natural killer cells from CD34+ hematopoietic progenitor cells
TL;DR: Data provide direct evidence that NK cells arise from CD34+HPC and show the minimum lymphokine requirement for their differentiation.