Kazusa Nishiyama

TL;DR: In vitro and in vivo results suggest that ATBC specifically induces CYP3A in the intestine by activating SXR, and acetyl tributyl citrate (ATBC), an industrial plasticizer widely used in products such as food wrap, vinyl toys, and pharmaceutical excipients, strongly activated human and rat SXR.

TL;DR: Since glycans containing the Galbeta1-4Fuc disaccharide unit have been found in organisms belonging to Protostomia, this unit might be a common glyco-epitope recognized by galectins in these organisms.

TL;DR: In this paper, the leaching of acetyl tributyl citrate (ATBC) from plastic kitchen wrap into water, aqueous acetic acid solution, and aaqueous skim milk solution heated to 60°C was investigated.

TL;DR: Results demonstrate the effectiveness of the T7 phage display environment for affinity selection of binding peptides and are expected to be extremely useful in the development of inhibitors or drug delivery systems targeting polysaccharides as well as further investigations into the function of carbohydrates in vivo.

TL;DR: A new strategy for synthesizing the labeled saccharides, in which the labeling unit, the 2-aminopyridine moiety, is coupled with a spacer unit derived from D-mannitol, indicates that Galbeta1-4Fuc is the endogenous glyco-epitope present in C. elegans N-glycans.