K
Keiichi Yoshimatsu
Researcher at University of California, Irvine
Publications - 36
Citations - 1509
Keiichi Yoshimatsu is an academic researcher from University of California, Irvine. The author has contributed to research in topics: Molecularly imprinted polymer & Molecular imprinting. The author has an hindex of 18, co-authored 34 publications receiving 1322 citations. Previous affiliations of Keiichi Yoshimatsu include Lund University & Missouri State University.
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Journal ArticleDOI
Uniform molecularly imprinted microspheres and nanoparticles prepared by precipitation polymerization: the control of particle size suitable for different analytical applications.
TL;DR: New synthetic conditions are initiated to obtain MIP beads with controllable size in the nano- to micro-meter range, using racemic propranolol as a model template, and the imprinted sites displayed high chiral selectivity.
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Temperature-responsive "catch and release" of proteins by using multifunctional polymer-based nanoparticles.
Keiichi Yoshimatsu,Benjamin K. Lesel,Yusuke Yonamine,John M. Beierle,Yu Hoshino,Kenneth J. Shea +5 more
TL;DR: This communication reports the synthesis and applications of a multifunctional polymer NP with selective protein affinity that can be modulated by external stimuli to “catch-and-release” the target protein.
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Selective molecular adsorption using electrospun nanofiber affinity membranes.
TL;DR: Using the new composite nan ofiber mats as solid phase extraction materials, trace amount of propranolol in tap water can be easily detected after a simple sample preparation and there is no problem of template leakage from the composite nanofibers.
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Characterization of QCM sensor surfaces coated with molecularly imprinted nanoparticles.
TL;DR: In this article, the authors functionalized quartz crystal microbalance (QCM) sensor crystals by coating the sensing surfaces with pre-made molecularly imprinted nanoparticles, which were immobilized on the QCM transducers by physical entrapment in a thin poly(ethylene terephthalate) (PET) layer that was spin-coated on the transducer surface.
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A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165).
Hiroyuki Koide,Keiichi Yoshimatsu,Yu Hoshino,Shih Hui Lee,Ai Okajima,Saki Ariizumi,Yudai Narita,Yusuke Yonamine,Adam Weisman,Yuri Nishimura,Naoto Oku,Yoshiko Miura,Kenneth J. Shea +12 more
TL;DR: Polymer NPs with nM affinity to a key vascular endothelial growth factor (VEGF165) inhibit binding of the signalling protein to its receptor VEGFR-2, preventing receptor phosphorylation and downstream VEGF165-dependent endothelial cell migration and invasion into the extracellular matrix.