Keith W. Singletary

TL;DR: Further progress in understanding alcohol's enhancing effect on breast cancer will depend on a better understanding of the interactions between alcohol and other risk factors and on additional insights into the multiple biological mechanisms involved.

TL;DR: In this paper, fruit extracts of four Vaccinium species (lowbush blueberry, bilberry, cranberry, and lingonberry) were screened for anticarcinogenic compounds by a combination of fractionation and in vitro testing of their ability to induce the Phase II xenobiotic detoxification enzyme quinone reductase (QR) and to inhibit the induction of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine synthesis, by the tumor promoter phorbol 12-myristate 13-acetate (

TL;DR: The results illustrate the potential of OCT for a wide range of basic research studies and for intra-operative image-guidance to identify foci of tumor cells within surgical margins during the surgical treatment of breast cancer.

TL;DR: New insights are provided into the signaling events that control induction of autophagy by B-group soyasaponins in human colon cancer cells and suggest that soyasalonins warrant further study as potential colon cancer chemopreventive agents.

TL;DR: Evidence is provided that SUL also acts as a breast cancer anti-proliferative agent and has mammary cancer suppressive actions both in cell culture and in the whole animal.