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Kekoolani S Visan
Researcher at QIMR Berghofer Medical Research Institute
Publications - 6
Citations - 31
Kekoolani S Visan is an academic researcher from QIMR Berghofer Medical Research Institute. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 1, co-authored 1 publications receiving 3 citations.
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Journal ArticleDOI
Comparative analysis of tangential flow filtration and ultracentrifugation, both combined with subsequent size exclusion chromatography, for the isolation of small extracellular vesicles
Kekoolani S Visan,Richard J. Lobb,Sunyoung Ham,Luize G. Lima,Carlos Palma,Chai Pei Zhi Edna,Li-ying Wu,Harsha T Gowda,Keshava K. Datta,Gunter Hartel,Carlos Salomon,Andreas Möller +11 more
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The role of exosomes in the promotion of epithelial-to-mesenchymal transition and metastasis.
TL;DR: The current state of research of exosomes in cancer EMT is presented, gaps in the current knowledge are highlighted and strategies for future experiments in this area are proposed.
Journal ArticleDOI
Blood-Derived Extracellular Vesicle-Associated miR-3182 Detects Non-Small Cell Lung Cancer Patients
Kekoolani S Visan,Richard J. Lobb,Shu Wen Wen,Justin Bedo,Luize G. Lima,Sophie Krumeich,Carlos Palma,Kaltin Ferguson,Benjamin Green,Colleen Niland,Nicole Cloonan,Peter T. Simpson,Amy E. McCart Reed,Sarah Everitt,Michael MacManus,Gunter Hartel,Carlos Salomon,Sunil R. Lakhani,David Fielding,Andreas Möller +19 more
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Status quo of Extracellular Vesicle isolation and detection methods for clinical utility.
TL;DR: Extracellular vesicles (EVs) are nano-sized particles that hold tremendous potential in the clinical space, as their biomolecular profiles hold a key to noninvasive liquid biopsy for cancer diagnosis and prognosis as mentioned in this paper .
Journal ArticleDOI
An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer
Richard J. Lobb,Kekoolani S Visan,Li-ying Wu,Emma L. Norris,Marcus L. Hastie,Sarah Everitt,Ian A. Yang,Rayleen V. Bowman,Shankar Siva,Jill E. Larsen,Jeffrey J. Gorman,Michael MacManus,Antoine Leimgruber,Kwun M. Fong,Andreas Möller +14 more
TL;DR: In this article , the phenotypic depolarization of epithelial cells to elongated mesenchymal cells, is associated with metastatic and treatment-refractive cancer.