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Carlos Salomon

Researcher at Royal Brisbane and Women's Hospital

Publications -  179
Citations -  8083

Carlos Salomon is an academic researcher from Royal Brisbane and Women's Hospital. The author has contributed to research in topics: Microvesicles & Exosome. The author has an hindex of 41, co-authored 158 publications receiving 5204 citations. Previous affiliations of Carlos Salomon include University of Los Andes & University of Concepción.

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Association between insulin resistance and the development of cardiovascular disease

TL;DR: It can be concluded that insulin resistance in the myocardium generates damage by at least three different mechanisms: (1) signal transduction alteration, (2) impaired regulation of substrate metabolism, and (3) altered delivery of substrates to theMyocardium.
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Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles.

TL;DR: The major biological functions, significance, and potential role of exosomes as biomarkers and therapeutics are discussed and an overview of the most commonly used techniques for exosome analysis, highlighting the major technical challenges and limitations of existing techniques, is presented.
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Placenta-derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy.

TL;DR: The number of exosomes present in the maternal plasma increased significantly with gestational age across the first trimester of pregnancy, and this study is a baseline that provides an ideal starting point for developing early detection method for women who subsequently develop pregnancy complications.
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A Gestational Profile of Placental Exosomes in Maternal Plasma and Their Effects on Endothelial Cell Migration

TL;DR: Changes in exosome profile may be of clinical utility in the diagnosis of placental dysfunction because pregnancy is associated with a dramatic increase in the number of exosomes present in plasma and maternal plasmaExosomes are bioactive.
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Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis.

TL;DR: The hypothesis that pMSC-derived exosomes may contribute to placental vascular adaptation to low oxygen tension under both physiological and pathological conditions is supported.