K
Kelly K. Lee
Researcher at Johns Hopkins University
Publications - 2
Citations - 323
Kelly K. Lee is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Polarizability. The author has an hindex of 2, co-authored 2 publications receiving 308 citations.
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Journal ArticleDOI
Experimental pKa Values of Buried Residues: Analysis with Continuum Methods and Role of Water Penetration
Carolyn A. Fitch,Daniel A. Karp,Kelly K. Lee,Wesley E. Stites,Eaton E. Lattman,E Bertrand García-Moreno +5 more
TL;DR: Calculations show that internal waters can modulate pK(a) values of buried residues effectively, and they support the hypothesis that the buried Lys-66 is in contact with internal waters even though these are not seen crystallographically.
Journal ArticleDOI
Distance dependence and salt sensitivity of pairwise, coulombic interactions in a protein
TL;DR: Histidine pKa values were measured in charge‐reversal and charge‐neutralization mutants of staphylococcal nuclease by 1H‐NMR spectroscopy to describe the distance dependence and salt sensitivity of pairwise coulombic interactions.