K
Kenneth P. Klinker
Researcher at University of Florida
Publications - 44
Citations - 999
Kenneth P. Klinker is an academic researcher from University of Florida. The author has contributed to research in topics: Cefepime & Antimicrobial stewardship. The author has an hindex of 16, co-authored 40 publications receiving 742 citations. Previous affiliations of Kenneth P. Klinker include UF Health Shands Hospital & University of Florida Health.
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Journal ArticleDOI
Clinical and economic impact of antimicrobial stewardship interventions with the FilmArray blood culture identification panel
Joe Pardo,Kenneth P. Klinker,Samuel J. Borgert,Brittany Butler,Patricia G. Giglio,Kenneth H. Rand +5 more
TL;DR: The BCID, coupled with antimicrobial stewardship intervention, was a cost effective tool to improve patient care and saved roughly $30,000 per 100 patients tested.
Journal ArticleDOI
Towards precision dosing of vancomycin: a systematic evaluation of pharmacometric models for Bayesian forecasting
A. Broeker,M. Nardecchia,Kenneth P. Klinker,Hartmut Derendorf,Richard O. Day,Deborah Marriott,Jane E. Carland,Jane E. Carland,Sophie L. Stocker,Sophie L. Stocker,Sebastian G. Wicha +10 more
TL;DR: The Goti model is revealed as suitable for improving precision dosing in hospitalized patients and should be used to drive vancomycin dosing decisions, and studies to link this finding to clinical outcomes are warranted.
Journal ArticleDOI
Large retrospective evaluation of the effectiveness and safety of ceftaroline fosamil therapy
Anthony M. Casapao,Susan L. Davis,Susan L. Davis,Viktorija O. Barr,Kenneth P. Klinker,Debra A. Goff,Debra A. Goff,Katie E. Barber,Keith S. Kaye,Keith S. Kaye,Ryan P. Mynatt,Leah Molloy,Jason M. Pogue,Jason M. Pogue,Michael J. Rybak,Michael J. Rybak,Michael J. Rybak +16 more
TL;DR: Clinical success was defined as resolution of all signs and symptoms of infection with no further need for escalation while on ceftaroline treatment during hospitalization, and hospital mortality was seen in 8% (40/527).
Journal ArticleDOI
Multicenter observational study of ceftaroline fosamil for methicillin-resistant Staphylococcus aureus bloodstream infections.
Evan J. Zasowski,Trang D Trinh,Kimberly C. Claeys,Kimberly C. Claeys,Anthony M. Casapao,Anthony M. Casapao,Noor Sabagha,Abdalhamid M Lagnf,Kenneth P. Klinker,Susan L. Davis,Susan L. Davis,Michael J. Rybak,Michael J. Rybak,Michael J. Rybak +13 more
TL;DR: Ceftaroline appears effective for MRSA BSI as both monotherapy and combination therapy, however, comparative studies are needed to further delineate the role of cephalosporin antibiotic with MRSA activity.
Journal ArticleDOI
Real-World Experience with Echinocandin MICs against Candida Species in a Multicenter Study of Hospitals That Routinely Perform Susceptibility Testing of Bloodstream Isolates
Gregory A. Eschenauer,M. Hong Nguyen,Shmuel Shoham,Jose A. Vazquez,Arthur J. Morris,William Pasculle,Christine J. Kubin,Kenneth P. Klinker,Peggy L. Carver,Kimberly E. Hanson,Sharon C.-A. Chen,Simon W. Lam,Brian A. Potoski,Lloyd Clarke,Ryan K. Shields,Cornelius J. Clancy,Cornelius J. Clancy +16 more
TL;DR: YeastOne assays employed in hospitals may reduce the interlaboratory variability in caspofungin MICs against Candida species that are observed between reference laboratories using CLSI broth microdilution methods.