K
Kevin E. Brown
Researcher at Public Health England
Publications - 191
Citations - 13467
Kevin E. Brown is an academic researcher from Public Health England. The author has contributed to research in topics: Parvovirus & Measles. The author has an hindex of 50, co-authored 191 publications receiving 9598 citations. Previous affiliations of Kevin E. Brown include National Institutes of Health & Health Protection Agency.
Papers
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Journal ArticleDOI
Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant.
Jamie Lopez Bernal,Nick Andrews,Charlotte Gower,Eileen Gallagher,Ruth Simmons,Simon Thelwall,Julia Stowe,Elise Tessier,Natalie Groves,Gavin Dabrera,Richard H. Myers,Colin Campbell,Gayatri Amirthalingam,Matt Edmunds,Maria Zambon,Kevin E. Brown,Susan Hopkins,Meera Chand,Mary Ramsay +18 more
TL;DR: The B.617.1.2 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes Coronavirus disease 2019 (Covid-19), has contributed to the development of the disease.
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Erythrocyte P antigen: cellular receptor for B19 parvovirus
TL;DR: The pathogenic human parvovirus B19 replicates only in erythroid progenitor cells and was shown to bind to blood-group P antigen, as measured by hemagglutination, which has implications for understanding the pathogenesis of parVovirus infections and for the use ofParvoviruses in gene therapy.
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Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative case-control study.
James Lopez Bernal,James Lopez Bernal,James Lopez Bernal,Nick Andrews,Nick Andrews,Charlotte Gower,Chris Robertson,Julia Stowe,Elise Tessier,Ruth Simmons,Simon Cottrell,Richard J. Roberts,Mark G. O'Doherty,Kevin E. Brown,Claire Cameron,Diane Stockton,Jim McMenamin,Mary Ramsay,Mary Ramsay +18 more
TL;DR: In this paper, Pfizer-BioNTech BNT162b2 and Oxford-AstraZeneca ChAdOx1-S vaccines against confirmed covid-19 symptoms (including the UK variant of concern B.1.7), admissions to hospital, and deaths.
Journal ArticleDOI
Human Parvovirus B19
Erik D. Heegaard,Kevin E. Brown +1 more
TL;DR: Parvovirus B19 was discovered in 1974 and is the only member of the family Parvoviridae known to be pathogenic in humans, anddiagnosis is primarily based on detection of specific antibodies by enzyme-linked immunosorbent assay or detection of viral DNA by dot blot hybridization or PCR.
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Adeno-Associated Virus Serotype 4 (AAV4) and AAV5 Both Require Sialic Acid Binding for Hemagglutination and Efficient Transduction but Differ in Sialic Acid Linkage Specificity
TL;DR: The results suggest that AAV4 and AAV5 require different sialic acid-containing glycoproteins for binding and transduction of target cells and they further explain the different tropism of AAV 4 and A AV5.