K
Kiichiro Tomoda
Researcher at Osaka Medical College
Publications - 33
Citations - 24267
Kiichiro Tomoda is an academic researcher from Osaka Medical College. The author has contributed to research in topics: Induced pluripotent stem cell & Stem cell. The author has an hindex of 18, co-authored 30 publications receiving 21439 citations. Previous affiliations of Kiichiro Tomoda include University of California, San Francisco & Gladstone Institutes.
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Journal ArticleDOI
Overexpression of Na+/H+ exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK
Shigeo Wakabayashi,Hirofumi Morihara,Shunichi Yokoe,Takatoshi Nakagawa,Kazumasa Moriwaki,Kiichiro Tomoda,Michio Asahi +6 more
TL;DR: NHE1 overexpression specifically induces death of iPSCs via sustained ROCK activation, probably caused by an increase in local pH near NHE1, and monensin, a Na+/H+ exchange ionophore, selectively killed iPSC colonies, suggesting that monens in could help eliminate i PSCs that remain after differentiation, a strategy that might be useful for improving regenerative medicine.
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ACVR1R206H extends inflammatory responses in human induced pluripotent stem cell-derived macrophages.
Koji Matsuo,Abigail Lepinski,Robert Dalton Chavez,Emilie Barruet,Ashley Pereira,Tania Moody,Amy N. Ton,Aditi Sharma,Judith Hellman,Kiichiro Tomoda,Mary C. Nakamura,Mary C. Nakamura,Edward C. Hsiao +12 more
TL;DR: In this article, 2D and 3D methods for directing human induced pluripotent stem cells (hiPSCs) into macrophages (iMACs) were described.
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Preparation and characterization of monoclonal antibodies against mouse Jab1/CSN5 protein.
Jun-ya Kato,Ikuko Nakamae,Kiichiro Tomoda,Akihisa Fukumoto,Akihisa Fukumoto,Noriko Yoneda-Kato +5 more
TL;DR: Five mouse monoclonal antibodies generated to a bacterially produced recombinant mouse Jab1 protein proved useful for immunohistochemical staining for Jab1 in fixed sections of human cancer samples, and should be useful in determining the expression and subcellular distribution of Jab 1 in human tumors.
Posted ContentDOI
Reprogramming Epiblast Stem Cells into Pre-Implantation Blastocyst Cell-like Cells
Kiichiro Tomoda,Kiichiro Tomoda,Haiming Hu,Yoshiki Sahara,Yoshiki Sahara,Hashimita Sanyal,Minoru Takasato,Cody Kime +7 more
TL;DR: This analysis confirms the induction of the extraembryonic cell populations during the reprogramming and anticipate that the unique BCLH SES and rich data may uncover new facets of cell potency, improve developmental biology, and help biomedicine advance.
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Synthetic embryology: Early mammalian embryo modeling systems from cell cultures.
TL;DR: Recently, the fields of embryology, developmental biology, stem cell biology, and cell reprogramming have intersected with synthetic embryo systems (SESs) from cultured cells.