K
Kiley Ariail
Publications - 2
Citations - 2566
Kiley Ariail is an academic researcher. The author has contributed to research in topics: Tumor necrosis factor alpha & Apoptosis. The author has an hindex of 2, co-authored 2 publications receiving 2491 citations.
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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
Henning Walczak,Robert E. Miller,Kiley Ariail,Brian Gliniak,Thomas S. Griffith,Marek Kubin,Wilson Chin,Jon Jones,Anne Woodward,Tiep Le,Craig A. Smith,Pam J. Smolak,Raymond G. Goodwin,Charles Rauch,JoAnn C. L. Schuh,David H. Lynch +15 more
TL;DR: Recurrent treatments with LZ–huTRAIL actively suppressed growth of the TRAIL–sensitive human mammary adenocarcinoma cell line MDA–231 in CB.17 (SCID) mice, and histologic examination of tumors from SCID mice treated with Lz–hu TRAIL demonstrated clear areas of apoptotic necrosis within 9–12 hours of injection.
Journal Article
Synergistic Action of fms-Like Tyrosine Kinase 3 Ligand and CD40 Ligand in the Induction of Dendritic Cells and Generation of Antitumor Immunity In Vivo
Luis G. Borges,Robert E. Miller,Jon Jones,Kiley Ariail,James Whitmore,William C. Fanslow,David H. Lynch +6 more
TL;DR: It is shown that Flt3L and CD40 ligand (CD40L) synergize in the generation of immune responses against two poorly immunogenic tumors, leading to complete tumor rejection in a high proportion of mice.