K
Kim B. Saunders
Researcher at Boston Children's Hospital
Publications - 6
Citations - 908
Kim B. Saunders is an academic researcher from Boston Children's Hospital. The author has contributed to research in topics: Endothelial stem cell & Endothelium. The author has an hindex of 5, co-authored 6 publications receiving 898 citations.
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An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes.
TL;DR: Results indicate that latent TGF-beta is produced by these cells and it is activated by a mechanism that requires contact between the two cell types, and it was demonstrated that activated T GF-beta produced in these cocultures mediates EC growth inhibition.
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An in vitro model for cell-cell interactions.
TL;DR: A co-culture system in which cells can be co-cultured across a porous membrane, permitting intercellular contact while maintaining pure cell populations, which should prove useful for the study of cell-cell interactions in a variety of systems.
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Heparin-mediated release of fibroblast growth factor-like activity into the circulation of rabbits.
TL;DR: The binding affinity of the plasma-derived stimulatory activity for heparin was used to demonstrate that the activity is FGF-like in nature.
Journal ArticleDOI
Alterations in gene expression associated with changes in the state of endothelial differentiation.
David T. Shima,David T. Shima,Kim B. Saunders,Anne Gougos,Patricia A. D'Amore,Patricia A. D'Amore +5 more
TL;DR: Use of differential display to study endothelial gene expression will allow us to investigate the molecular mechanisms that underlie initiation and maintenance of endothelial differentiation.