K
Kimberly A. Russell
Researcher at Oregon Health & Science University
Publications - 4
Citations - 247
Kimberly A. Russell is an academic researcher from Oregon Health & Science University. The author has contributed to research in topics: Pichia pastoris & Peroxisome. The author has an hindex of 3, co-authored 4 publications receiving 242 citations.
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PER3, a Gene Required for Peroxisome Biogenesis in Pichia pastoris, Encodes a Peroxisomal Membrane Protein Involved in Protein Import
TL;DR: The cloning of PER3 and functional characterization of its product Per3p suggest that the vesicles in per3-1 cells are peroxisomal remnants similar to those observed in cells of patients with the peroxISomal disorder Zellweger syndrome, and that the mutant is deficient in PTS1 but not PTS2 import.
Journal ArticleDOI
Peroxisomal Targeting, Import, and Assembly of Alcohol Oxidase in Pichia pastoris
TL;DR: AOX cannot initiate oligomerization in the cytoplasm, but must first be targeted to the organelle before assembly begins, suggesting that newly synthesized AOX–HA cannot oligomerize with wild-type AOX (AOX-WT).
Journal Article
The Pichia pastoris PER6 gene product is a peroxisomal integral membrane protein essential for peroxisome biogenesis and has sequence similarity to the Zellweger syndrome protein PAF-1
Hans R. Waterham,Yne de Vries,Kimberly A. Russell,Weiqiao Xie,Marten Veenhuis,James M. Cregg +5 more
TL;DR: The similarities between Per6p and PAF-1 in amino acid sequence and biochemical properties, and between mutants defective in their respective genes, suggest that Per 6p is the putative yeast homolog of PAF -1.