K
Kimitoshi Kohno
Researcher at University of Occupational and Environmental Health Japan
Publications - 282
Citations - 17228
Kimitoshi Kohno is an academic researcher from University of Occupational and Environmental Health Japan. The author has contributed to research in topics: Transcription factor & Cell culture. The author has an hindex of 73, co-authored 282 publications receiving 16423 citations. Previous affiliations of Kimitoshi Kohno include Northwestern University & Kyushu University.
Papers
More filters
Journal ArticleDOI
Cellular pH regulators: potentially promising molecular targets for cancer chemotherapy
Hiroto Izumi,Takayuki Torigoe,Hiroshi Ishiguchi,Hidetaka Uramoto,Yoichiro Yoshida,Mizuho Tanabe,Tomoko Ise,Tadashi Murakami,Takeshi Yoshida,Minoru Nomoto,Kimitoshi Kohno +10 more
TL;DR: Understanding pH regulation in tumour cells may provide new ways of inducing tumour-specific apoptosis, thus aiding cancer chemotherapy.
Journal ArticleDOI
The pleiotropic functions of the Y-box-binding protein, YB-1.
TL;DR: This review will begin by briefly describing the characteristics of YB-1 and will then summarize the pleiotropic functions brought about via DNA-RNA transaction and protein-protein interactions, which will discuss the diverse range of potential physiological and pathological functions of YBs.
Journal ArticleDOI
Induction of Vascular Endothelial Growth Factor by Tumor Necrosis Factor α in Human Glioma Cells POSSIBLE ROLES OF SP-1
Masahiro Ryuto,Mayumi Ono,Hiroto Izumi,Shigeo Yoshida,Herbert A. Weich,Kimitoshi Kohno,Michihiko Kuwano +6 more
TL;DR: The chloramphenicol acetyltransferase assay with VEGF promoter deletion constructs demonstrated that four clusterized SP-1 binding sites in the proximal promoter were essential for the basal transcription and the TNF-α-dependent activation.
Journal Article
A Human Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene Is Overexpressed in Cisplatin-resistant Human Cancer Cell Lines with Decreased Drug Accumulation
Ken Taniguchi,Morimasa Wada,Kimitoshi Kohno,Takanori Nakamura,T Kawabe,Mina Kawakami,Kazuhiro Kagotani,Katsuzumi Okumura,Shin-ichi Akiyama,Michihiko Kuwano +9 more
TL;DR: The cDNA of a new ATP binding cassette superfamily that was specifically enhanced in a cisplatin-resistant human head and neck cancer KB cell line was isolated and a human clone homologous to rat canalicular multispecific organic anion transporter (cMOAT) was found and designated human cMOAT.
Journal Article
Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors.
Ken Samoto,Kiyonobu Ikezaki,Mayumi Ono,Tadahisa Shono,Kimitoshi Kohno,Michihiko Kuwano,Masashi Fukui +6 more
TL;DR: It is suggested that VEGF may be a positive factor in tumor angiogenesis in both human gliomas and meningiomas.