Kimon Stamatelopoulos

TL;DR: Coffee exerts an acute unfavourable effect on the endothelial function in healthy adults, lasting for at least 1 h after intake, which might be attributed to caffeine.

TL;DR: Whether these beneficial arterial changes are direct effects of the IL-6/IL-6 receptor pathway inhibition, maintained over time and translate into better clinical outcome warrants further studies.

TL;DR: Accumulating evidence supports the utility of non-invasive markers of subclinical atherosclerosis, namely carotid intimal media thickness, flow mediated dilatation of the brachial artery, augmentation index or pulse wave velocity, in the prediction of cardiovascular risk particularly in primary prevention settings.

TL;DR: The role of platelet-derived chemokines in inflammation and atherosclerosis is focused on and the clinical value of plasma levels of chemokine in the prognosis of atherosclerotic heart disease is discussed.

TL;DR: In this paper, the authors discuss SARS-CoV-2 life cycle and a number of approaches aiming to suppress viral infection rates or propagation; increase virus antigen presentation in order to activate a robust and durable adaptive immune response from the host, and/or mitigate the ARDS-related "cytokine storm" and collateral tissue damage that triggers the severe life-threatening complications of COVID-19.