Kira Yanowsky

TL;DR: The identification of deregulated miRNAs in plasma of patients with breast cancer supports the use of circulating mi RNAs as a method for early breast cancer detection.

TL;DR: Evidence is provided that telomere shortening is associated with earlier age of cancer onset in successive generations of affected families, suggesting that it might be a mechanism of genetic anticipation in hereditary breast cancer.

TL;DR: Evidence is provided that KRAS is a target of miR-30c, and that this miRNA suppresses breast cancer cell growth potentially through inhibition of KRAS signaling, suggesting common underlying mechanisms of tumor progression.

TL;DR: The results indicate that miR-498 regulates BRCA1 expression in breast cancer and its overexpression could contribute to the pathogenesis of sporadic TNBC via B RCA1 downregulation.

TL;DR: Findings indicate that TL could be a risk factor for early onset ovarian cancer, and both sporadic and hereditary cases showed significantly shorter age adjusted TLs than controls.