K
Kiran Kumar
Researcher at All India Institute of Medical Sciences
Publications - 57
Citations - 624
Kiran Kumar is an academic researcher from All India Institute of Medical Sciences. The author has contributed to research in topics: Medicine & Diabetes mellitus. The author has an hindex of 12, co-authored 48 publications receiving 532 citations.
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Journal ArticleDOI
Chronic renal insufficiency among Asian Indians with type 2 diabetes: I. Role of RAAS gene polymorphisms
Pushplata Prasad,Arun K. Tiwari,Kiran Kumar,Ariachery C. Ammini,Arvind Gupta,Rajeev Gupta,A. K. Sharma,Atmakuri Ramakrishna Rao,R. Nagendra,T. Satish Chandra,S. C. Tiwari,Priyanka Rastogi,B Lal Gupta,B.K. Thelma +13 more
TL;DR: SNPs Met235Thr in angiotensinogen, T>C (-344) in aldosterone synthase, and G>A (-1903) in chymase genes are significantly associated with diabetic chronic renal insufficiency in Indian patients and warrant replication in larger sample sets.
Journal ArticleDOI
Association of TGFβ1, TNFα, CCR2 and CCR5 gene polymorphisms in type-2 diabetes and renal insufficiency among Asian Indians
Pushplata Prasad,Arun K. Tiwari,Kiran Kumar,Ariachery C. Ammini,Arvind Gupta,Rajeev Gupta,B.K. Thelma +6 more
TL;DR: Of the various cytokine gene polymorphisms tested, allele 59029A of CCR5 gene is significantly associated with diabetic renal insufficiency among Asian Indians, in conformity with reports from a Japanese population.
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Oxidative stress pathway genes and chronic renal insufficiency in Asian Indians with Type 2 diabetes
Arun K. Tiwari,Pushplata Prasad,B.K. Thelma,Kiran Kumar,Ariachery C. Ammini,Arvind Gupta,Rajeev Gupta +6 more
TL;DR: The nonreplication of association suggests differential genetic susceptibility of the two populations to diabetic chronic renal insufficiency and oxidative stress pathway genes might be an important predictor for the development of diabetic complications.
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Association analysis of ADPRT1, AKR1B1, RAGE, GFPT2 and PAI-1 gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.
Pushplata Prasad,Arun K. Tiwari,Kiran Kumar,Ariachery C. Ammini,Arvind Gupta,Rajeev Gupta,B.K. Thelma +6 more
TL;DR: Association of SNPs in RAGE and GFPT2 suggest that the genes involved in modulation of oxidative pathway could be major contributor to diabetic chronic renal insufficiency and G FPT2 could be a relevant target for pharmacological intervention.
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Association of dopaminergic pathway gene polymorphisms with chronic renal insufficiency among Asian Indians with type-2 diabetes.
TL;DR: Some polymorphisms in DRD2 and COMT genes are significantly associated with susceptibility to CRI in the Asian Indian population which, if confirmed, would be consistent with a suggested role of dopamine metabolism in disease occurrence.