K
Kishor Mandaliya
Researcher at University of Washington
Publications - 55
Citations - 2398
Kishor Mandaliya is an academic researcher from University of Washington. The author has contributed to research in topics: Viral load & Population. The author has an hindex of 25, co-authored 55 publications receiving 2161 citations.
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Journal ArticleDOI
HIV-1 drug resistance in antiretroviral-naive individuals in sub-Saharan Africa after rollout of antiretroviral therapy: a multicentre observational study
Raph L. Hamers,Carole L. Wallis,Cissy Kityo,Margaret Siwale,Kishor Mandaliya,Francesca Conradie,Mariette E. Botes,Maureen Wellington,Akin Osibogun,Kim C. E. Sigaloff,Immaculate Nankya,Rob Schuurman,Ferdinand W. N. M. Wit,Wendy S. Stevens,Michèle van Vugt,Tobias F. Rinke de Wit +15 more
TL;DR: The higher prevalence of primary drug resistance in Uganda than in other African countries is probably related to the earlier start of ART roll-out in Uganda.
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Unnecessary Antiretroviral Treatment Switches and Accumulation of HIV Resistance Mutations; Two Arguments for Viral Load Monitoring in Africa
Kim C. E. Sigaloff,Raph L. Hamers,Carole L. Wallis,Cissy Kityo,Margaret Siwale,Prudence Ive,Mariette E. Botes,Kishor Mandaliya,Maureen Wellington,Akin Osibogun,Wendy S. Stevens,Michèle van Vugt,Tobias F. Rinke de Wit +12 more
TL;DR: Prolonged treatment failure was indicated by extensive NRTI cross-resistance and access to virological monitoring should be expanded to prevent inappropriate switches, enable early failure detection and preserve second-line treatment options in Africa.
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Effect of pretreatment HIV-1 drug resistance on immunological virological and drug-resistance outcomes of first-line antiretroviral treatment in sub-Saharan Africa: a multicentre cohort study.
Raph L. Hamers,Rob Schuurman,Kim C. E. Sigaloff,Carole L. Wallis,Cissy Kityo,Margaret Siwale,Kishor Mandaliya,Prudence Ive,Mariette E. Botes,Maureen Wellington,Akin Osibogun,Ferdinand W. N. M. Wit,Michèle van Vugt,Wendy S. Stevens,Tobias F. Rinke de Wit +14 more
TL;DR: Improved access to alternative combinations of antiretroviral drugs in sub-Saharan Africa is warranted and improved access to alternatives to pretreatment drug resistance is warranted.
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Patterns of HIV-1 Drug Resistance After First-Line Antiretroviral Therapy (ART) Failure in 6 Sub-Saharan African Countries: Implications for Second-Line ART Strategies
Raph L. Hamers,Kim C. E. Sigaloff,Annemarie M. J. Wensing,Carole L. Wallis,Cissy Kityo,Margaret Siwale,Kishor Mandaliya,Prudence Ive,Mariette E. Botes,Maureen Wellington,Akin Osibogun,Wendy S. Stevens,Tobias F. Rinke de Wit,Rob Schuurman +13 more
TL;DR: After stavudine failure in African populations, zidovudine rather than tenofovir may be preferred in second-line ART, and early failure detection limited the accumulation of resistance.
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Mother-to-child HIV transmission in resource poor settings: how to improve coverage?
TL;DR: The coverage of perinatal MTCT in Coast Provincial General Hospital in Mombasa, Kenya was low as a result of a variety of programme elements requiring urgent improvement at different levels, and alternative models, including intrapartum testing, should be considered as a safety net for women without access to VCT before delivery.