Klaus B. Heller

TL;DR: A close correlation could be demonstrated between leak formation and phospholipid peroxidation as monitored by occurrence of malondialdehyde, and the two processes showed similar dependences on exposure time, concentration and temperature.

TL;DR: It is demonstrated that a mere pulse treatment of erythrocytes with t-butylhydroperoxide leads to subsequent development of progressive oxidative membrane damage in spite of the absence of exogenous oxidant.

TL;DR: It is proposed that radical formation originates from reduction of O2 by NADPH, analogous to processes described in microsomal membranes, and vanadate and ferricyanide are probably required to amplify the peroxidative reaction sufficiently to overcome the cellular antioxidative capacity.

TL;DR: Findings indicate that formation of disulfide bonds by different oxidative mechanisms results in leaks with similar properties and are reconcilable with the formation of aqueous pores.

TL;DR: The temperature dependence of the active monosaccharide transport across the cell membrane of the yeastRhodotorula gracilis is studied and a sharp “break” occurs in the Arrhenius plot and with increasing temperature the transport becomes inactivated, with a positive slope of the corresponding straight line.