K
Klaus D. Zang
Researcher at Saarland University
Publications - 73
Citations - 2502
Klaus D. Zang is an academic researcher from Saarland University. The author has contributed to research in topics: Fluorescence in situ hybridization & Meningioma. The author has an hindex of 27, co-authored 73 publications receiving 2422 citations.
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Novel immunogenic antigen homologous to hyaluronidase in meningioma
TL;DR: A model for involvement of the novel hyaluronidase gene in meningioma development is proposed and four cDNA clones representing a novel gene with striking homology to Caenorhabditis elegans hyaluridase are identified.
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p53 and c-Jun Functionally Synergize in the Regulation of the DNA Repair Gene hMSH2 in Response to UV
Stefan J. Scherer,Stefan J. Scherer,Sandra M. Maier,Markus Seifert,Rainer G. Hanselmann,Klaus D. Zang,Hans K. Müller-Hermelink,Peter Angel,Cornelius Welter,Manfred Schartl +9 more
TL;DR: The synergistic interaction of a proto-oncogene with a tumor suppresser gene is required for the regulation of the mammalian stress response through activation of expression of MSH2.
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Evidence of Focal Genetic Microheterogeneity in Glioblastoma Multiforme by Area-Specific CGH on Microdissected Tumor Cells
Volker Jung,Bernd F. M. Romeike,Wolfram Henn,Wolfgang Feiden,Jean Richard Moringlane,Klaus D. Zang,Steffi Urbschat +6 more
TL;DR: Evidence of considerable intratumoral genetic heterogeneity in glioblastoma multiforme is given and microdissection provides a sensitive tool for the detection of quantitative chromosomal changes that are present only regionally within a given tumor.
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Predictive value of progression-associated chromosomal aberrations for the prognosis of meningiomas: a retrospective study of 198 cases
Ralf Ketter,Wolfram Henn,Isolde Niedermayer,Heike Steilen-Gimbel,Jochem König,Klaus D. Zang,Wolf-Ingo Steudel +6 more
TL;DR: The cytogenetic classification of meningiomas provides a significant contribution to the predictability of tumor recurrence and is, therefore, a valuable criterion for the neurosurgeon's postoperative management protocol.