M
Manfred Schartl
Researcher at University of Würzburg
Publications - 504
Citations - 25224
Manfred Schartl is an academic researcher from University of Würzburg. The author has contributed to research in topics: Xiphophorus & Gene. The author has an hindex of 76, co-authored 487 publications receiving 22485 citations. Previous affiliations of Manfred Schartl include National Institute for Basic Biology, Japan & École normale supérieure de Lyon.
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Journal ArticleDOI
Gene and genome duplications in vertebrates: the one-to-four (-to-eight in fish) rule and the evolution of novel gene functions.
Axel Meyer,Manfred Schartl +1 more
TL;DR: The increased genetic complexity of fish might reflect their evolutionary success and diversity, and many others evolved new functions particularly during development.
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A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes
Indrajit Nanda,Mariko Kondo,Ute Hornung,Shuichi Asakawa,Christoph Winkler,Atsushi Shimizu,Zhihong Shan,Thomas Haaf,Nobuyoshi Shimizu,Akihiro Shima,Michael Schmid,Manfred Schartl +11 more
TL;DR: It is found that in the fish medaka the Y chromosome-specific region spans only about 280 kb and contains a duplicated copy of the autosomal DMRT1 gene, named D MRT1Y, which is the only functional gene in this chromosome segment and maps precisely to the male sex-determining locus.
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Medaka — a model organism from the far east
TL;DR: In this paper, the authors introduce the use of fish as model genetic systems to study gene function in the context of vertebrate development, using the Zebrafish as a model vertebrate and its Far Eastern cousin Medaka as an important model fish.
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Whole-genome sequence of a flatfish provides insights into ZW sex chromosome evolution and adaptation to a benthic lifestyle
Songlin Chen,Guojie Zhang,Changwei Shao,Quanfei Huang,Geng Liu,Pei Zhang,Wentao Song,Na An,Domitille Chalopin,Jean-Nicolas Volff,Yunhan Hong,Qiye Li,Zhenxia Sha,Heling Zhou,Mingshu Xie,Qiulin Yu,Yang Liu,Hui Xiang,Na Wang,Kui Wu,Yang Changgeng,Qian Zhou,Xiaolin Liao,Linfeng Yang,Qiaomu Hu,Jilin Zhang,Liang Meng,Lijun Jin,Yongsheng Tian,Jinmin Lian,Jing-Feng Yang,Guidong Miao,Shanshan Liu,Zhuo Liang,Fang Yan,Yangzhen Li,Bin Sun,Hong Zhang,Jing Zhang,Ying Zhu,Min Du,Yongwei Zhao,Manfred Schartl,Qi-Sheng Tang,Jun Wang +44 more
TL;DR: It is found that massive gene loss occurred in the wake of sex-chromosome 'birth' in Cynoglossus semilaevis, and the sex chromosomes of these fish are derived from the same ancestral vertebrate protochromosome as the avian W and Z chromosomes.
Journal ArticleDOI
The African coelacanth genome provides insights into tetrapod evolution
Chris T. Amemiya,Chris T. Amemiya,Jessica Alföldi,Alison P. Lee,Shaohua Fan,Hervé Philippe,Iain MacCallum,Ingo Braasch,Tereza Manousaki,Igor Schneider,Nicolas Rohner,Chris L. Organ,Domitille Chalopin,J. Joshua Smith,Mark Robinson,Rosemary A. Dorrington,Marco Gerdol,Bronwen Aken,Maria Assunta Biscotti,Marco Barucca,Denis Baurain,Aaron M. Berlin,Gregory L. Blatch,Gregory L. Blatch,Francesco Buonocore,Thorsten Burmester,Michael S. Campbell,Adriana Canapa,John P. Cannon,Alan Christoffels,Gianluca De Moro,Adrienne L. Edkins,Lin Fan,Anna Maria Fausto,Nathalie Feiner,Mariko Forconi,Junaid Gamieldien,Sante Gnerre,Andreas Gnirke,Jared V. Goldstone,Wilfried Haerty,Mark E. Hahn,Uljana Hesse,Steve Hoffmann,Jeremy Johnson,Sibel I. Karchner,Shigehiro Kuraku,Marcia Lara,Joshua Z. Levin,Gary W. Litman,Evan Mauceli,Evan Mauceli,Tsutomu Miyake,M. Gail Mueller,David R. Nelson,Anne Nitsche,Ettore Olmo,Tatsuya Ota,Alberto Pallavicini,Sumir Panji,Barbara Picone,Chris P. Ponting,Sonja J. Prohaska,Dariusz Przybylski,Nil Ratan Saha,Vydianathan Ravi,Filipe J. Ribeiro,Tatjana Sauka-Spengler,Giuseppe Scapigliati,Stephen M. J. Searle,Ted Sharpe,Oleg Simakov,Peter F. Stadler,John J. Stegeman,Kenta Sumiyama,Diana Tabbaa,Hakim Tafer,Jason Turner-Maier,Peter van Heusden,Simon D. M. White,Louise Williams,Mark Yandell,Henner Brinkmann,Jean Nicolas Volff,Clifford J. Tabin,Neil H. Shubin,Manfred Schartl,David B. Jaffe,John H. Postlethwait,Byrappa Venkatesh,Federica Di Palma,Eric S. Lander,Axel Meyer,Kerstin Lindblad-Toh,Kerstin Lindblad-Toh +94 more
TL;DR: Through a phylogenomic analysis, it is concluded that the lungfish, and not the coelacanth, is the closest living relative of tetrapods.