Showing papers by "Klaus M. Hahn published in 1991"

TL;DR: Derivatives of colchicine and the bicyclic col chicine analog 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone were tested for inhibition of tubulin polymerization and the nature of the tropone substituent had litte effect on the efficacy of the colchichine series, with some exceptions.

TL;DR: Advantages of DIAZOPY-SE as a photoaffinity labeling reagent include ease of synthesis, chemical and photostability, efficient photolysis at wavelengths greater than 300 nm, and a capacity for crosslinking by carbene insertion processes.