Klaus M. Pedersen

TL;DR: The data indicate that each individual had a unique thyroid function, and the distinction between subclinical and overt thyroid disease (abnormal serum TSH and abnormal T(4) and/or T(3)) is somewhat arbitrary.

TL;DR: Thyroid abnormalities in populations with low iodine intake and those with high iodine intake develop in opposite directions: goiter and thyroid hyperfunction when iodine intake is relatively low, and impaired thyroid function when iodine Intake is relatively high.

TL;DR: In this paper, the authors compared the incidence of different types of hyperthyroidism in East-Jutland Denmark with a low average iodine intake but no endemic goitre, and the incidence in Iceland with a relatively high iodine intake.

TL;DR: A longitudinal study of sixteen healthy men living in an area of mild to moderate iodine deficiency was performed in this paper. And the number of urine samples needed to determine the iodine excretion level for crude urinary iodine and for 24-hour iodine consumption from age and gender-specific creatinine excretions was calculated.

TL;DR: Serum TSH responds with amplification to minor alterations in T(4) and T(3), which underlines the importance of TSH in diagnosis and monitoring of thyroid dysfunctions and implies that subclinical thyroid disease may be defined in purely biochemical terms.