K
Konrad Thorner
Publications - 4
Citations - 26
Konrad Thorner is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 1, co-authored 1 publications receiving 17 citations.
Papers
More filters
Journal ArticleDOI
CAR-T Engineering: Optimizing Signal Transduction and Effector Mechanisms
Emiliano Roselli,Jeremy S. Frieling,Konrad Thorner,Maria C. Ramello,Conor C. Lynch,Daniel Abate-Daga +5 more
TL;DR: Modifications in the intracellular domain of the CAR that gave rise to first, second, third- and next-generation CAR-T cells are summarized and the structure of the antigen-sensing ectodomain can be enhanced, leading to superiorCAR-T cell signaling and/or function.
Journal ArticleDOI
Identification of a heterogeneous and dynamic ciliome during embryonic development and cell differentiation
Kelsey H. Elliott,Sai Keshavan Balchand,C. L. Bonatto Paese,Ching-Fang Chang,Yanfen Yang,Kari M. Brown,Daniel T. Rasicci,Hao He,Konrad Thorner,Praneet Chaturvedi,Stephen A. Murray,Jian Chen,Aleksey Porollo,Kevin A. Peterson,Samantha A. Brugmann +14 more
TL;DR: This article provided a searchable transcriptomic resource for a curated primary ciliome, detailing various subgroups of differentially expressed genes within the Ciliome that display tissue and temporal specificity.
Journal ArticleDOI
Use of phage display biopanning as a tool to design CAR-T cells against glioma stem cells
Marine Potez,Sebastian Snedal,Chunhua She,Jongmyung Kim,Konrad Thorner,Timothy H. Tran,María Cecilia Ramello,Daniel Abate-Daga,James K. Liu +8 more
TL;DR: In this article , the authors used phage display biopanning for the isolation of GSC-targeting peptides, and their potential application in the development of novel cytotoxic therapies for GBM.
Journal ArticleDOI
Transplanted human intestinal organoids: a resource for modeling human intestinal development
Akaljot Singh,Holly M. Poling,Praneet Chaturvedi,Konrad Thorner,Nambirajan Sundaram,Daniel O. Kechele,Charlie Childs,Heather A. McCauley,Garrett W Fisher,Nicole Brown,Jason R. Spence,James A. Wells,Michael A. Helmrath +12 more
TL;DR: In this paper , a time course of transplanted HIOs histologically at 2, 4, 6 and 8 weeks post-transplantation was analyzed, and it was shown that HIO maturation closely resembles key stages of fetal human intestinal development.