K
Konstantin Christov-Tselkov
Researcher at University of Illinois at Chicago
Publications - 1
Citations - 1253
Konstantin Christov-Tselkov is an academic researcher from University of Illinois at Chicago. The author has contributed to research in topics: Genotoxic Stress & Radiation therapy. The author has an hindex of 1, co-authored 1 publications receiving 1205 citations.
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A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
Pavel G. Komarov,Elena A. Komarova,Roman V. Kondratov,Konstantin Christov-Tselkov,John S. Coon,Mikhail V. Chernov,Andrei V. Gudkov +6 more
TL;DR: This study has shown that a small molecule isolated for its ability to reversibly block p53-dependent transcriptional activation and apoptosis protected mice from the lethal genotoxic stress associated with anticancer treatment without promoting the formation of tumors.