K
Konstantinos Ritis
Researcher at Democritus University of Thrace
Publications - 100
Citations - 16641
Konstantinos Ritis is an academic researcher from Democritus University of Thrace. The author has contributed to research in topics: Neutrophil extracellular traps & Familial Mediterranean fever. The author has an hindex of 40, co-authored 91 publications receiving 12890 citations. Previous affiliations of Konstantinos Ritis include Umeå University.
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Journal ArticleDOI
Methylation status of RASSF1A in patients with chronic myeloid leukemia.
Antigoni Avramouli,Stefanos Tsochas,Eudokia Mandala,Eirini Katodritou,Maria Ioannou,Konstantinos Ritis,Matthaios Speletas +6 more
TL;DR: The findings indicate that RASSF1A methylation does not appear to represent a critical step in the pathogenesis and/or the progression of CML.
Journal ArticleDOI
Interferon regulatory factor-1 (IRF-1) suppression and derepression during endometrial tumorigenesis and cancer progression.
Alexandra Giatromanolaki,Michael I. Koukourakis,Konstantinos Ritis,Konstantinos Mimidis,Efthimios Sivridis +4 more
TL;DR: It is concluded that down-regulation of IRF-1 is a constant finding in endometrial tumorigenesis, however, derepression of IRf-1 may occur in a subset of tumors, and this event is associated with TP up-regulation and aggressive tumor behavior.
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Survivin isoform expression patterns in CML patients correlate with resistance to imatinib and progression, but do not trigger cytolytic responses.
Matthaios Speletas,Nikoletta Argentou,Vaios Karanikas,Evangelia S. Gramoustianou,Eudokia Mandala,Margarita Braimi,Panagiota Matsouka,Konstantinos Ritis,Anastasios E. Germenis +8 more
TL;DR: In this article, the role of survivin isoform expression and specific CD8(+) T cells in CML was investigated, and the results question the validity of immunotherapeutic approaches targeting survivin.
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Mast cells co-expressing CD68 and inorganic polyphosphate are linked with colorectal cancer.
Stella Arelaki,Athanasios Arampatzioglou,Konstantinos Kambas,Efthimios Sivridis,Alexandra Giatromanolaki,Konstantinos Ritis +5 more
TL;DR: Surgical specimens from CRC were examined to investigate the presence of polyP, as a possible NET inducer, and the detection of CD68+ polyP-expressing mast cells could represent a potential prognostic marker in colorectal adenomas and/or carcinomas.
Journal ArticleDOI
TLR2 and TLR4 polymorphisms in familial Mediterranean fever.
Matthaios Speletas,Fani Kalala,Ioannis Mitroulis,V Papadopoulos,Vassiliki Merentiti,Anastasios E. Germenis,Konstantinos Ritis +6 more
TL;DR: The results may reinforce the hypothesis that FMF patients display a better defense against pathogens, providing an additional mechanism and suggesting a positive selection advantage in the area of the Mediterranean basin.