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Kooi-Mow Sim

Researcher at Universiti Tunku Abdul Rahman

Publications -  40
Citations -  908

Kooi-Mow Sim is an academic researcher from Universiti Tunku Abdul Rahman. The author has contributed to research in topics: Tabernaemontana corymbosa & Tabernaemontana. The author has an hindex of 18, co-authored 38 publications receiving 846 citations. Previous affiliations of Kooi-Mow Sim include University of Malaya.

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Alkaloids from Kopsia griffithii

TL;DR: In this paper, 19 alkaloids were isolated from the leaf extract of Kopsia griffithii, of which two were new, viz., 12-methoxypleiocarpine and the tetrahydro-β-carboline derivative, harmicine.
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Leishmanicidal alkaloids from Kopsia griffithii

TL;DR: Thirteen alkaloids were isolated from the stem-bark extract of Kopsia griffithii, of which three were new, and Harmane, pleiocarpine and buchtienine showed antileishmanial activity.
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Cytotoxic and Leishmanicidal Aminoglycosteroids and Aminosteroids from Holarrhena curtisii

TL;DR: The EtOH extract of the leaves of Holarrhena curtisii yielded five new steroidal alkaloids and eight compounds showed significant cytotoxic and leishmanicidal activities.
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Leuconoxine, kopsinitarine, kopsijasmine, and kopsinone derivatives from Kopsia.

TL;DR: Four new indole alkaloids were obtained from two Kopsia species, 6-oxoleuconoxine from the leaf extract of K. griffithii and kopsinitarine E, and kopsonoline from the stem-bark extract ofK.
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Tronocarpine, a novel pentacyclic indole incorporating a seven-membered lactam moiety

TL;DR: A pentacyclic indole alkaloid, tronocarpine, incorporating a seven-membered lactam unit, was obtained from the stem-bark extract of Tabernaemontana corymbosa and its structure elucidated by spectral analysis.