Journal ArticleDOI
Alkaloids from Kopsia griffithii
Toh-Seok Kam,Kooi-Mow Sim +1 more
TLDR
In this paper, 19 alkaloids were isolated from the leaf extract of Kopsia griffithii, of which two were new, viz., 12-methoxypleiocarpine and the tetrahydro-β-carboline derivative, harmicine.About:
This article is published in Phytochemistry.The article was published on 1998-01-01. It has received 116 citations till now.read more
Citations
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Simple indole alkaloids and those with a nonrearranged monoterpenoid unit
Tomomi Kawasaki,Kazuhiro Higuchi +1 more
TL;DR: This review covers the literature on simple indole alkaloid and those with a nonrearranged monoterpenoid unit and newly isolated alkaloids, structure determinations, total syntheses and biological activities.
Journal ArticleDOI
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit
Satoshi Hibino,Tominari Choshi +1 more
TL;DR: This review covers the literature on simple indole alkaloid and those with a nonrearranged monoterpenoid unit from the beginning of 2012 up to the end of 2013, which includes newly isolated alkaloids, structure determinations, total syntheses and biological activities.
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Asymmetric organocatalysis in total synthesis – a trial by fire
TL;DR: This aim is to showcase how organocatalytic reactions have overcome some of their teething problems and how they frequently offer very practical solutions to long-standing synthetic challenges.
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Pd(II)-catalyzed meta-C-H olefination, arylation, and acetoxylation of indolines using a U-shaped template
Guoqiang Yang,Petra Lindovska,Dajian Zhu,Justin Kim,Peng Wang,Ri-Yuan Tang,Mohammad Movassaghi,Jin-Quan Yu +7 more
TL;DR: A wide range of synthetically important and advanced indoline analogues are selectively functionalized at the meta-positions because of the combination of a monoprotected amino acid ligand and the nitrile template attached at the indolinyl nitrogen via a sulfonamide linkage.
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Engineering an enantioselective amine oxidase for the synthesis of pharmaceutical building blocks and alkaloid natural products.
Diego Ghislieri,Anthony P. Green,Marta Pontini,Simon C. Willies,Ian Rowles,Annika Frank,Gideon Grogan,Nicholas J. Turner +7 more
TL;DR: A "toolbox" of monoamine oxidase variants from Aspergillus niger (MAO-N) which display remarkable substrate scope and tolerance for sterically demanding motifs are described, including a new variant, which exhibits high activity and enantioselectivity toward substrates containing the aminodiphenylmethane (benzhydrylamine) template.
References
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Journal ArticleDOI
Lundurines A, B and C, new indole alkaloids with a novel carbon skeleton containing a cyclopropyl moiety
TL;DR: In this article, three new indole alkaloids (Lundurines A, B and C) possessing a novel carbon skeleton incorporating a cyclopropyl unit were obtained from Kopsia tenuis.
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Alkaloids of leuconotis griffithii and L. Eugenifolia (Apocynaceae)
TL;DR: Leuconotis griffithii and L. eugenifolia provided a variety of Strychnos and Aspidosperma-Hunteria alkaloid as well as novel ring-opened indole alkaloids including leuconolam and 5,21-dihydrorhazinilam, which led to ring reclosure products.
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The c-3 configuration of certain indole alkaloids1
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Plumeran alkaloids from Kopsia profunda
Toh-Seok Kam,Poh-Suan Tan +1 more
TL;DR: Two new plumeran alkaloids, N -methoxycarbonyl-11,12-methylenedioxy-Δ 16,17 -kopsinine and N -Methoxy carbonyl - 12-meth oxygen-Γ 16, 17 -kopinine, have been isolated from the stem of Kopsia profunda.
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Indole alkaloids from leaves and stems of Leuconotis eugenifolius
Fumiko Abe,Tatsuo Yamauchi +1 more
TL;DR: A new alkaloid was determined to be a diazaspiroleuconolam and named leuconoxine and other constituents identified were 3β-hydroxy-5α,6α-epoxy-β-ionone, epigallocatechin, loganic acid, 2-methyl-3-buten-2-ol rutinoside and four flavonol glycosides.