K
Kostas A. Papavassiliou
Researcher at National and Kapodistrian University of Athens
Publications - 40
Citations - 965
Kostas A. Papavassiliou is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 11, co-authored 21 publications receiving 629 citations.
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Journal ArticleDOI
Pivotal Role of STAT3 in Shaping Glioblastoma Immune Microenvironment.
TL;DR: Current experimental and clinical evidence that highlights the pivotal role of STAT3 in glioma tumorigenesis and particularly in shaping tumor immune microenvironment in an effort to justify the high need of selective targeting for gliomas immunotherapy are discussed.
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Targeting Androgen/Estrogen Receptors Crosstalk in Cancer
Michalis V. Karamouzis,Kostas A. Papavassiliou,Christos Adamopoulos,Athanasios G. Papavassiliou +3 more
TL;DR: The molecular background regarding the therapeutic targeting of androgen/estrogen receptor crosstalk in breast and prostate cancer is discussed, which comprises a dynamic regulatory network enhancing or limiting the activity of AR-directed treatments in breast
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Polycystin-1 and polycystin-2 are involved in the acquisition of aggressive phenotypes in colorectal cancer.
Antonios N. Gargalionis,Penelope Korkolopoulou,Elena Farmaki,Christina Piperi,Georgia Dalagiorgou,Christos Adamopoulos,Georgia Levidou,Angelica A. Saetta,Paraskevi C. Fragkou,Panagiota Tsioli,Hippokratis Kiaris,Adamantia Zizi-Serbetzoglou,Ioannis Karavokyros,Kostas A. Papavassiliou,Nikolaos Tsavaris,Efstratios Patsouris,Efthimia K. Basdra,Athanasios G. Papavassiliou +17 more
TL;DR: Results support a direct link between mechanosensing polycystins (PC1 and PC2) and CRC progression, and appear to support a independent prognostic factor of reduced recurrence‐free survival.
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Systemic effects of AGEs in ER stress induction in vivo
Christos Adamopoulos,Chrysovalantou Mihailidou,Christofora Grivaki,Kostas A. Papavassiliou,Hippokratis Kiaris,Christina Piperi,Athanasios G. Papavassiliou +6 more
TL;DR: In vivo studies undertaken by this group and others that demonstrate the diverse systemic effects of AGEs in ER stress induction in major metabolic tissues such as brain, kidney, liver and pancreas of normal mice are described.
Journal ArticleDOI
Targeting STAT3 Signaling Pathway in Colorectal Cancer.
TL;DR: Signal transducer and activator of transcription 3 (STAT3) is a critical transcription factor that has been firmly associated with colorectal cancer initiation and development.