K
Kouichi Yabiku
Researcher at University of the Ryukyus
Publications - 10
Citations - 367
Kouichi Yabiku is an academic researcher from University of the Ryukyus. The author has contributed to research in topics: Brown rice & Graves' disease. The author has an hindex of 7, co-authored 10 publications receiving 326 citations.
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Journal ArticleDOI
Brown Rice and Its Component, γ-Oryzanol, Attenuate the Preference for High-Fat Diet by Decreasing Hypothalamic Endoplasmic Reticulum Stress in Mice
Chisayo Kozuka,Kouichi Yabiku,Sumito Sunagawa,Rei Ueda,Shin-ichiro Taira,Hiroyuki Ohshiro,Tomomi Ikema,Ken Yamakawa,Moritake Higa,Hideaki Tanaka,Chitoshi Takayama,Masayuki Matsushita,Seiichi Oyadomari,Michio Shimabukuro,Hiroaki Masuzaki +14 more
TL;DR: This is the first demonstration that brown rice and Orz improve glucose metabolism, reduce hypothalamic ER stress, and, consequently, attenuate the preference for dietary fat in mice fed an HFD.
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Natural food science based novel approach toward prevention and treatment of obesity and type 2 diabetes: recent studies on brown rice and γ-oryzanol.
Chisayo Kozuka,Kouichi Yabiku,Chitoshi Takayama,Masayuki Matsushita,Michio Shimabukuro,Hiroaki Masuzaki +5 more
TL;DR: This paper found that one of the major components of brown rice, γ-oryzanol (Orz), plays an important role in the metabolically beneficial effects of brown Rice and showed that Orz acts as a chemical chaperone and decreases high fat diet (HFD)-induced endoplasmic reticulum (ER) stress in the hypothalamus.
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Effects of the brown rice diet on visceral obesity and endothelial function: the BRAVO study.
Michio Shimabukuro,Moritake Higa,Rie Kinjo,Ken Yamakawa,Hideaki Tanaka,Chisayo Kozuka,Kouichi Yabiku,Shin-ichiro Taira,Masataka Sata,Hiroaki Masuzaki +9 more
TL;DR: Consumption of BR may be beneficial, partly owing to the lowering of glycaemic response, and may protect postprandial endothelial function in subjects with the metabolic syndrome.
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Remission of Graves' hyperthyroidism and A/G polymorphism at position 49 in exon 1 of cytotoxic T lymphocyte-associated molecule-4 gene.
Yoshino Kinjo,Nobuyuki Takasu,Ichiro Komiya,Takeaki Tomoyose,Masaki Takara,Tsuyoshi Kouki,Yoshinori Shimajiri,Kouichi Yabiku,Hiroshi Yoshimura +8 more
TL;DR: In this paper, the authors studied whether a patient with Graves' disease will go into remission during antithyroid drug (ATD) treatment, which is predicted by a smooth decrease in TSH receptor antibody (TRAb) during ATD treatment.
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Cytotoxic T-lymphocyte antigen-4 gene polymorphisms and human T-cell lymphotrophic virus-1 infection: their associations with Hashimoto's thyroiditis in Japanese patients.
Takeaki Tomoyose,Ichiro Komiya,Masaki Takara,Kouichi Yabiku,Yoshino Kinjo,Yoshinori Shimajiri,Hiroyuki Yogi,Tsuyoshi Kouki,Masato Masuda,Nobuyuki Takasu +9 more
TL;DR: Genetic polymorphisms involving CTLA-4 promoter, exon 1 (49 A/G), and exon 4 (microsatellite (AT)n) have been linked to Hashimoto's thyroiditis (HT) and other autoimmune diseases, and HTLV-1 infection is not regulated by genetic factor, and may affect occurrence of HT as an independent purely environmental factor.