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Krzysztof Trzciński

Researcher at Utrecht University

Publications -  83
Citations -  4999

Krzysztof Trzciński is an academic researcher from Utrecht University. The author has contributed to research in topics: Streptococcus pneumoniae & Pneumococcal infections. The author has an hindex of 37, co-authored 75 publications receiving 4339 citations. Previous affiliations of Krzysztof Trzciński include University of Warwick & University Medical Center Utrecht.

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Viral and bacterial interactions in the upper respiratory tract.

TL;DR: A theoretical model is proposed to summarize and illustrate mechanisms by which specific bacterial–bacterial and viral-bacterial interactions that occur in the upper respiratory niche might be mediated and provide better insight into the pathogenesis of respiratory diseases.
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CD4+ T cells mediate antibody-independent acquired immunity to pneumococcal colonization

TL;DR: It is found that immunity to pneumococcal colonization can be induced in the absence of antibody, independent of the capsular type, and this protection requires the presence of CD4(+) T cells at the time of challenge.
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Pneumococcal Capsular Polysaccharide Structure Predicts Serotype Prevalence

TL;DR: An association between increased carriage prevalence and resistance to non-opsonic neutrophil-mediated killing is found and non-vaccine serotypes that have become common in vaccinated populations tend to be those with fewer carbons per repeat units and low energy expended per repeat unit, suggesting a novel biological principle to explain patterns of serotype replacement.
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Expression of resistance to tetracyclines in strains of methicillin-resistant Staphylococcus aureus

TL;DR: This study suggests that, despite the results of susceptibility testing, all tetracycline-resistant S. aureus isolates should be treated as resistant to doxycycline, and all tetM-positive isolatesshould be treatedAs resistant to all termacyclines.
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Interference between Streptococcus pneumoniae and Staphylococcus aureus: In Vitro Hydrogen Peroxide-Mediated Killing by Streptococcus pneumoniae

TL;DR: Catalase eliminated the bactericidal activity of Streptococcus pneumoniae toward Staphylococcus aureus and provided a possible mechanistic explanation for the interspecies interference observed in epidemiologic studies.