Kuo-Wei Chen

TL;DR: The real-time LightCycler assay aiming at rapid detection and species identification of pathogenic fungi from clinical isolates was developed and is simple, rapid and sensitive enough for detection and identification of several fungal species.

TL;DR: The result showed that the DNA type of each isolate was patient specific and associated with ABC type and decade of isolation but not associated with mating type, anatomical source of isolation, hospital origin, or fluconazole resistance patterns.

TL;DR: The investigation of the genetic profiles of 53 Candida albicans isolates collected from 18 hospitals in Taiwan using three PFGE-based typing methods (PFGE karyotyping, and PFGE of SfiI and BssHII restriction fragments) and one repetitive-sequence-PCR (rep- PCR) method showed that the genotype of each isolate was patient-specific and not associated with the source of the isolation, geographic origin or antifungal resistance.

TL;DR: The genotypes, sequence types, and mating type classes were independent of anatomic sources, drug susceptibility, and HIV infection status and exhibited less discriminatory power than PFGE with BssHII.

TL;DR: Antifungal susceptibility tests showed that most isolates were susceptible to flucytosine, azoles, amphotericin B, and echinocandins, whereas 3 C. metapsilosis isolates from 1 patient showed resistance and susceptible-dose dependence to fluconazole.