Kurt Tobler

TL;DR: Results indicate that heterodimeric fusion protein containing a truncated form of ORF3 was produced in high amounts, carried the expected OrF3 epitope, showed phosphatase activity, and was able to bind to the GM1 receptor, indicating that it may have biological activity in prokaryotes.

TL;DR: This study addressed the impact of gM/UL49.5-specific regions on heterodimer formation, folding and trafficking from the endoplasmic reticulum (ER) to the trans-Golgi network (TGN) and found that leucine substitutions in putative glycine zipper motifs within TM helices ofgM resulted in strong reduction of complex formation and decreased ability of g M to interfere with UL49.

TL;DR: It is shown that Rep68 can bind to consensus Rep-binding sites on the HSV-1 genome and that the Rep helicase activity can inhibit replication of any DNA if binding is facilitated.

TL;DR: Based on the dinucleotide frequencies IBV gained a position in between of the TGEV-related and the MHV-clustered coronaviruses, which roughly reflect the taxonomic groups.

TL;DR: The nature and possible functions of the conserved sequence motifs are discussed, and the application of these sequences to viral genome amplification is concentrated on in this article.