K
Kyoung-Youl Lee
Researcher at Kongju National University
Publications - 61
Citations - 864
Kyoung-Youl Lee is an academic researcher from Kongju National University. The author has contributed to research in topics: Neurotrophic factors & Offspring. The author has an hindex of 17, co-authored 60 publications receiving 813 citations. Previous affiliations of Kyoung-Youl Lee include Kagawa University.
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Journal ArticleDOI
Diverse developmental toxicity of di-n-butyl phthalate in both sexes of rat offspring after maternal exposure during the period from late gestation through lactation.
Kyoung-Youl Lee,Makoto Shibutani,Hironori Takagi,Natsumi Kato,Shu Takigami,Chikako Uneyama,Masao Hirose +6 more
TL;DR: Developmental exposure to DBP affected female sexual development involving pituitary function, while in males testicular toxicity was mostly reversible but mammary gland toxicity was persistent at a dose level as low as 20 ppm.
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Application of the physical disector to the central nervous system: Estimation of the total number of neurons in subdivisions of the rat hippocampus
Takanori Miki,Irawan Satriotomo,Hong-Peng Li,Yoshiki Matsumoto,He Gu,Toshifumi Yokoyama,Kyoung-Youl Lee,Kuldip S. Bedi,Yoshiki Takeuchi +8 more
TL;DR: The methods used for this evaluation were, first, the Cavalieri principle, which was used to determine the volumes of the various subdivisions of the rat hippocampus, and, second, the ‘physical disector’ method, whichwas used to estimate the numerical density of neurons within each subdivision.
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Microdissected Region-specific Gene Expression Analysis with Methacarn-fixed, Paraffin-embedded Tissues by Real-time RT-PCR
Hironori Takagi,Makoto Shibutani,Natsumi Kato,Haruka Fujita,Kyoung-Youl Lee,Shu Takigami,Kunitoshi Mitsumori,Kunitoshi Mitsumori,Masao Hirose +8 more
TL;DR: High performance with methacarn is indicated, close to that of unfixed tissues, regarding quantitative expression analysis of mRNAs in microdissected PET-specimens using a real-time RT-PCR technique.
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Subchronic toxicity study of dietary N-acetylglucosamine in F344 rats
Kyoung-Youl Lee,Makoto Shibutani,Hironori Takagi,Takuro Arimura,Shu Takigami,Chikako Uneyama,Natsumi Kato,Masao Hirose +7 more
TL;DR: It was concluded that orally administered GlcNAc exerts no obvious toxicity to F344 rats at concentrations up to 5% in the diet for 13 weeks, translating into 2476 and 2834 mg/kg/day for male and female rats, respectively.
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Effects of maternal exposure to di(2-ethylhexyl)phthalate (DEHP) during pregnancy on susceptibility to neonatal asthma
TL;DR: It is suggested that maternal exposure to DEHP during pregnancy reduces asthmatic responses induced by OVA challenge in offspring, with a decrease in inducible nitric oxide synthase (iNOS) in the lung tissue.