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L. Di Vito

Researcher at University of Turin

Publications -  25
Citations -  1342

L. Di Vito is an academic researcher from University of Turin. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 12, co-authored 18 publications receiving 1313 citations.

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Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone.

TL;DR: Ghrelin, a natural ligand of GHS-receptor, exerts a strong stimulatory effect on GH secretion in humans, releasing more GH than GHRH and even more than a nonnatural GHS such as HEX, which possesses strong GH-releasing activity but also significantly stimulates PRL, ACTH, and cortisol secretion.
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Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans.

TL;DR: An endogenous ligand for the GH secretagogue-receptor (GHS-R) has been recently purified from rat and human stomach and named Ghrelin exerted a strong stimulatory effect on GH secretion in humans releasing more GH than GHRH.
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Retesting young adults with childhood-onset growth hormone (GH) deficiency with GH-releasing-hormone-plus-arginine test.

TL;DR: G HRH + arginine (GHRH+ARG) is the most reliable alternative to the insulin-induced hypoglycemia test (ITT) as a provocative test for the diagnosis of GHD in adulthood, provided that appropriate cut-off limits are assumed.
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Low dose (1 μg) ACTH test in the evaluation of adrenal dysfunction in pre-clinical Addison's disease

TL;DR: The clinical use of the low‐dose ACTH test (LDT) in the diagnosis of early adrenocortical dysfunction in patients with adrenal autoantibodies was evaluated.
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The GH, prolactin, ACTH and cortisol responses to Hexarelin, a synthetic hexapeptide, undergo different age-related variations

TL;DR: It is demonstrated that in humans the GH- and ACTH-releasing activities of HEX undergo different age-related variations, and actions at different levels and/or on different hormonal subtypes of GHRPs are suggested.