E
Emanuela Arvat
Researcher at University of Turin
Publications - 306
Citations - 12641
Emanuela Arvat is an academic researcher from University of Turin. The author has contributed to research in topics: Growth hormone secretion & Somatostatin. The author has an hindex of 55, co-authored 289 publications receiving 11884 citations. Previous affiliations of Emanuela Arvat include University of Bari & University of Milan.
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Journal ArticleDOI
Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.
Fabio Broglio,Emanuela Arvat,Andrea Benso,C. Gottero,Giampiero Muccioli,Mauro Papotti,Aart Jan van der Lely,Romano Deghenghi,Ezio Ghigo +8 more
TL;DR: Findings show that, besides stimulating GH secretion, ghrelin is a gastric hormone possessing metabolic actions such as hyperglycemic effect and lowering effect on insulin secretion in humans, at least after acute administration.
Journal ArticleDOI
Adjuvant mitotane treatment for adrenocortical carcinoma.
Massimo Terzolo,Alberto Angeli,Martin Fassnacht,Fulvia Daffara,Libuse Tauchmanovà,Pier Antonio Conton,R. Rossetto,Lisa Buci,Paola Sperone,Erika Grossrubatscher,Giuseppe Reimondo,Enrico Bollito,Mauro Papotti,Wolfgang Saeger,Stefanie Hahner,Ann Cathrin Koschker,Emanuela Arvat,Bruno Ambrosi,Paola Loli,Gaetano Lombardi,Massimo Mannelli,Paolo Bruzzi,Franco Mantero,Bruno Allolio,Luigi Dogliotti,Alfredo Berruti +25 more
TL;DR: Adjuvant mitotane treatment had a significant advantage for recurrence-free survival in patients with radically resected adrenocortical carcinoma, and temporary dose reduction was needed in 13% of patients.
Journal ArticleDOI
Endocrine activities of ghrelin, a natural growth hormone secretagogue (GHS), in humans: comparison and interactions with hexarelin, a nonnatural peptidyl GHS, and GH-releasing hormone.
Emanuela Arvat,M. Maccario,L. Di Vito,Fabio Broglio,Andrea Benso,C. Gottero,M Papotti,Giampiero Muccioli,C. Dieguez,Felipe F. Casanueva,Romano Deghenghi,F. Camanni,Ezio Ghigo +12 more
TL;DR: Ghrelin, a natural ligand of GHS-receptor, exerts a strong stimulatory effect on GH secretion in humans, releasing more GH than GHRH and even more than a nonnatural GHS such as HEX, which possesses strong GH-releasing activity but also significantly stimulates PRL, ACTH, and cortisol secretion.
Journal ArticleDOI
Preliminary evidence that Ghrelin, the natural GH secretagogue (GHS)-receptor ligand, strongly stimulates GH secretion in humans.
Emanuela Arvat,L. Di Vito,Fabio Broglio,Mauro Papotti,Giampiero Muccioli,Carlos Dieguez,Felipe F. Casanueva,Romano Deghenghi,Franco Camanni,Ezio Ghigo +9 more
TL;DR: An endogenous ligand for the GH secretagogue-receptor (GHS-R) has been recently purified from rat and human stomach and named Ghrelin exerted a strong stimulatory effect on GH secretion in humans releasing more GH than GHRH.
Journal ArticleDOI
Comparison between insulin-induced hypoglycemia and growth hormone (GH)-releasing hormone + arginine as provocative tests for the diagnosis of GH deficiency in adults.
Gianluca Aimaretti,G. Corneli,P. Razzore,S. Bellone,Claudia Baffoni,Emanuela Arvat,Franco Camanni,Ezio Ghigo +7 more
TL;DR: The present results confirm that the ITT test is a reliable provocative test for the diagnosis of adult GHD, whereas they show that the GHRH + ARG test is, at least, as sensitive as the ITt test (provided that appropriate cut-off limits are considered).