L
L. Harinantenaina Rakotondraibe
Researcher at Ohio State University
Publications - 23
Citations - 260
L. Harinantenaina Rakotondraibe is an academic researcher from Ohio State University. The author has contributed to research in topics: Cinnamosma fragrans & Cinnamosma. The author has an hindex of 8, co-authored 20 publications receiving 167 citations.
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Journal ArticleDOI
Halogenated Compounds from Directed Fermentation of Penicillium concentricum, an Endophytic Fungus of the Liverwort Trichocolea tomentella
Tehane Ali,Masanori Inagaki,Heebyung Chai,Thomas F. Wieboldt,Chad Rapplye,L. Harinantenaina Rakotondraibe +5 more
TL;DR: It is confirmed that the brominated gentisyl alcohol was formed by chemical conversion of 4 during bromide salt addition to culture media and exhibited selective cytotoxicity against the HT-29 colon cancer cell line with an IC50 value of 6.4 μM.
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Antiproliferative Constituents of the Roots of Ethiopian Podocarpus falcatus and Structure Revision of 2α-Hydroxynagilactone F and Nagilactone I.
Ermias Mekuria Addo,Ermias Mekuria Addo,Heebyung Chai,Ariaya Hymete,Mariamawit Yonathan Yeshak,Carla Slebodnick,David G. I. Kingston,L. Harinantenaina Rakotondraibe +7 more
TL;DR: Among the isolated compounds, the nagilactones, including the new dilactones 16-hydroxynagilACTone F (1) and 2β,16-dihydroxynAGilact one F (2), were the most active against the HT-29 cell line, whereas the bisditerpenoids and the other known compounds 9 and 10 were inactive.
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A natural agonist of mosquito TRPA1 from the medicinal plant Cinnamosma fragrans that is toxic, antifeedant, and repellent to the yellow fever mosquito Aedes aegypti
Edna Alfaro Inocente,Marguerite Shaya,Nuris M. Acosta,L. Harinantenaina Rakotondraibe,Peter M. Piermarini +4 more
TL;DR: The study suggests that CDIAL may serve as a novel chemical platform for the development of natural product-based insecticides and repellents for controlling mosquito vectors.
Journal ArticleDOI
Bioactive drimane sesquiterpenoids and aromatic glycosides from Cinnamosma fragrans.
TL;DR: A preliminary SAR study showed that the hydroxyl group at C-12' and the presence of conjugated carbonyl contribute to the antiproliferative activity of 17.
Journal ArticleDOI
Antiproliferative and antiplasmodial compounds from selected Streptomyces species.
L. Harinantenaina Rakotondraibe,Rado Rasolomampianina,Hyun Young Park,Jie Li,Carla Slebodnik,Peggy J. Brodie,Leah C. Blasiak,Russel T. Hill,Karen TenDyke,Yongchun Shen,Maria B. Cassera,Felicite Rejo,David G. I. Kingston +12 more
TL;DR: Bioassay-guided fractionation coupled with dereplication of the active extracts led to the identification and isolation of nonactin (1), monactsin (2), dinactin(3), ±-nonactic acid (4), toyocamycin (5), piperafizine A (6) and a new dipeptide named xestostreptin (7).